Evidence map›Paper›PMID 19221522›Full record

ReviewPrion

The elaborate structure of spider silk: structure and function of a natural high performance fiber.

Lin Römer, Thomas Scheibel

Open access · bronzeAbstract readReview
In one paragraph

Review in Prion. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 372 citations in OpenAlex.

  1. Coacervates as bio-inspired intermediates for materials processing.Chemical communications (Cambridge, England) · 2026
    Review
  2. Article
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. An analysis of silk density in spider webs.Royal Society open science · 2025
    Article
  11. Article
  12. Article
  13. A Bio-Inspired Perspective on Materials Sustainability.Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Organ-resolved lipid mapping inFrontiers in chemistry · 2025
    Article
  20. High-yield spidroin mimics for bioinspired fibers via computational design.Frontiers in bioengineering and biotechnology · 2025
    Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lin RömerUniversität Bayreuth, Fakultät für angew. Naturwissenschaften, Lehrstuhl für Biomaterialien, Bayreuth, Germany.
Thomas Scheibel
University of Bayreuth · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomaterials, having evolved over millions of years, often exceed man-made materials in their properties. Spider silk is one outstanding fibrous biomaterial which consists almost entirely of large proteins. Silk fibers have tensile strengths comparable to steel and some silks are nearly as elastic as rubber on a weight to weight basis. In combining these two properties, silks reveal a toughness that is two to three times that of synthetic fibers like Nylon or Kevlar. Spider silk is also antimicrobial, hypoallergenic and completely biodegradable. This article focuses on the structure-function relationship of the characterized highly repetitive spider silk spidroins and their conformational conversion from solution into fibers. Such knowedge is of crucial importance to understanding the intrinsic properties of spider silk and to get insight into the sophisticated assembly processes of silk proteins. This review further outlines recent progress in recombinant production of spider silk proteins and their assembly into distinct polymer materials as a basis for novel products.

Indexed as

AnimalsModels, BiologicalSilkSpidersStructure-Activity RelationshipSilk

Identifiers

PMID19221522
PMCPMC2658765
OpenAlexW1603396702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.