ArticleMolecular and cellular biology1991
Cloning of a growth arrest-specific and transforming growth factor beta-regulated gene, TI 1, from an epithelial cell line.
Article in Molecular and cellular biology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 38 citations in OpenAlex.
- Uroplakins in urothelial biology, function, and disease.Kidney international · 2009Review
- Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases.The Journal of cell biology · 2004Article
- Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum.Molecular biology of the cell · 2002Article
- Uroplakin gene expression by normal and neoplastic human urothelium.The American journal of pathology · 1998Article
- Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctions.The Journal of cell biology · 1998Article
- SFA-1, a novel cellular gene induced by human T-cell leukemia virus type 1, is a member of the transmembrane 4 superfamily.Journal of virology · 1996Article
- Interactions among regulators of RNA abundance characterized using RNA fingerprinting by arbitrarily primed PCR.Nucleic acids research · 1994Article
- The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells.Molecular and cellular biology · 1994Article
- Uroplakins Ia and Ib, two major differentiation products of bladder epithelium, belong to a family of four transmembrane domain (4TM) proteins.The Journal of cell biology · 1994Article
- Association of four antigens of the tetraspans family (CD37, CD53, TAPA-1, and R2/C33) with MHC class II glycoproteins.Immunogenetics · 1994Article
- Chromosomal localization of uroplakin genes of cattle and mice.Mammalian genome : official journal of the International Mammalian Genome Society · 1993Article
- Genomic structure of the human CD53 gene.Immunogenetics · 1993Article
- Regulation and expression of a growth arrest-specific gene (gas5) during growth, differentiation, and development.Molecular and cellular biology · 1992Article
- Expression of a growth arrest specific gene (gas-1) in transformed cells.British journal of cancer · 1992Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
By cDNA cloning and differential screening, five genes that are regulated by transforming growth factor beta (TGF beta) in mink lung epithelial cells were identified. A novel membrane protein gene, TI 1, was identified which was downregulated by TGF beta and serum in quiescent cells. In actively growing cells, the TI 1 gene is rapidly and transiently induced by TGF beta, and it is overexpressed in the presence of protein synthesis inhibitors. It appears to be related to a family of transmembrane glycoproteins that are expressed on lymphocytes and tumor cells. The four other genes were all induced by TGF beta and correspond to the genes of collagen alpha type I, fibronectin, plasminogen activator inhibitor 1, and the monocyte chemotactic cell-activating factor (JE gene) previously shown to be TGF beta regulated.
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