Evidence map›Paper›PMID 19218386›Full record

ArticleJournal of bacteriology2009

Differential expression of sigH paralogs during growth and under different stress conditions in Mycobacterium smegmatis.

Anirudh K Singh, Bhupendra N Singh

Abstract read
In one paragraph

Article in Journal of bacteriology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Dynamic Transcriptional Landscape ofInternational journal of molecular sciences · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anirudh K SinghDivision of Microbiology, Central Drug Research Institute, Lucknow 226 001, India. bhupendransingh@gmail.com
Bhupendra N Singh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SigH regulates a transcriptional network that responds to heat and oxidative stress in mycobacteria. Seven sigH paralogs are reported to exist in the Mycobacterium smegmatis genome. A comprehensive real-time reverse transcriptase PCR analysis during different stages of growth and upon exposure to various stress conditions and antimycobacterial compounds showed differential expression of sigH paralogs during stationary phase and severalfold increases in the levels of transcription of sigH1, sigH4, sigH5, sigH6, and sigH7 under specific stress conditions.

Indexed as

Gene Expression ProfilingGene Expression Regulation, BacterialAntitubercular AgentsBacterial ProteinsGene OrderGenes, BacterialHot TemperatureMycobacterium smegmatisOxidative StressProtein IsoformsSigma FactorAntitubercular AgentsBacterial ProteinsProtein IsoformsSigH protein, bacteriaSigma Factor

Identifiers

PMID19218386
PMCPMC2668427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.