ReviewThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry2009
Ocular dominance columns: enigmas and challenges.
Review in The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 54 citations in OpenAlex.
- Retinotopic remapping of the visual system in deaf adults.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The grand challenge in cellular neurophysiology.Frontiers in cellular neuroscience · 2026Article
- A Critical Look at Critical Periods.Annual review of vision science · 2025Review
- Improving Adult Vision Through Pathway-Specific Training in Augmented Reality.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Interocular suppression in chromoluminance patterns measured with SSVEP.Journal of vision · 2025Article
- Harnessing brain plasticity to improve binocular vision in amblyopia: An evidence-based update.European journal of ophthalmology · 2024Review
- The causal involvement of the visual cortex in visual working memory remains uncertain.Royal Society open science · 2024Article
- Development of ocular dominance columns across rodents and other species: revisiting the concept of critical period plasticity.Frontiers in neural circuits · 2024Review
- Isochronic development of cortical synapses in primates and mice.Nature communications · 2023Article
- A role for ocular dominance in binocular integration.Current biology : CB · 2023Article
- Ocular Dominance and Its Association With Central Corneal Thickness: An Observational Study in Central India.Cureus · 2023Article
- What has vision science taught us about functional MRI?NeuroImage · 2022Article
- Eye-specific pattern-motion signals support the perception of three-dimensional motion.Journal of vision · 2019Article
- Strategies for assembling columns and layers in the Drosophila visual system.Neural development · 2018Review
- Maximizing sensitivity for fast GABA edited spectroscopy in the visual cortex at 7 T.NMR in biomedicine · 2018Article
- Universal transition from unstructured to structured neural maps.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Review
- The marmoset monkey as a model for visual neuroscience.Neuroscience research · 2015Review
- Visual cortical areas of the mouse: comparison of parcellation and network structure with primates.Frontiers in neural circuits · 2014Review
- Deletion of Ten-m3 induces the formation of eye dominance domains in mouse visual cortex.Cerebral cortex (New York, N.Y. : 1991) · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
In some mammalian species, geniculocortical afferents serving each eye are segregated in layer 4C of striate cortex into stripes called ocular dominance columns. Having described the complete pattern of ocular dominance columns in the human brain, the authors enumerate here the principal enigmas that confront future investigators. Probably the overarching challenge is to explain the function, if any, of ocular dominance columns and why they are present in some species and not others. A satisfactory solution must account for the enormous natural variation, even within the same species, among individuals in column expression, pattern, periodicity, and alignment with other components of the functional architecture. Another major priority is to explain the development of ocular dominance columns. It has been established clearly that they form without visual experience, but the innate signals that guide their segregation and maturation are unknown. Experiments addressing the role of spontaneous retinal activity have yielded contradictory data. These studies must be reconciled, to pave the way for new insights into how columnar structure is generated in the cerebral cortex.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.