Evidence map›Paper›PMID 19218023›Full record

ReviewEmergency medicine clinics of North America2009

Enhancing community delivery of tissue plasminogen activator in stroke through community-academic collaborative clinical knowledge translation.

Phillip A Scott

Registry-linked trialAbstract readReview
In one paragraph

Review in Emergency medicine clinics of North America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00349479 (Clinical Trial to Increase t-PA Use in Stroke Treatment), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00349479 nacompletednot on this map

Clinical Trial to Increase t-PA Use in Stroke Treatment

TypeinterventionalSponsorUniversity of MichiganRan2005 to 2010Enrolled24ConditionsStrokeArmsBarrier assessment / interactive educational intervention
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Phillip A ScottDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MI 48106-0381, USA. phlsctt@med.umich.edu

Funding

Clinical Trial to Increase tPA Use in Stroke TreatmentR01NS050372 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCOTT, PHILLIP · 2005 to 2010
$3.2M
NINDS NIH HHS R01 NS050372NINDS NIH HHS R01 NS50372
6 · The paper itself

Abstract

Improving the clinical outcomes of stroke patients depends on the adoption of proven new therapies throughout the broader medical community. Approximately 1% of stroke patients in community settings are receiving tissue plasminogen activator (tPA) therapy 12 years after US Food and Drug Administration approval. Knowledge translation, the process by which the results of clinical investigations are adopted by clinicians and incorporated into routine practice, is important but often overlooked. This article reviews the history of tPA use in stroke as a case study of a breakdown of knowledge translation in emergency medicine. It reviews knowledge translation concepts and theory and explores practical community-academic collaborative methods based on these tenets to enhance acute stroke care delivery in the community setting.

Indexed as

Clinical CompetenceClinical ProtocolsCrisis InterventionDrug ApprovalEducation, Medical, ContinuingEvidence-Based MedicineFeedback, PsychologicalHumansInternship and ResidencyPractice Guidelines as TopicResuscitationSelf EfficacyStrokeTissue Plasminogen ActivatorTissue Plasminogen Activator

Identifiers

PMID19218023
PMCPMC2674264

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.