ReviewNeurogastroenterology and motility2009
Genetic model system studies of the development of the enteric nervous system, gut motility and Hirschsprung's disease.
Review in Neurogastroenterology and motility, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Preclinical Models of Neuroendocrine Neoplasia.Cancers · 2022Review
- The enteric nervous system in gastrointestinal disease etiology.Cellular and molecular life sciences : CMLS · 2021Review
- MicroRNA-939 inhibits cell proliferation via targeting LRSAM1 in Hirschsprung's disease.Aging · 2017Article
- Effects of RET, NRG1 and NRG3 Polymorphisms in a Chinese Population with Hirschsprung Disease.Scientific reports · 2017Article
- Article
- White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies.Developmental biology · 2016Review
- Nanocrystalline cerium dioxide efficacy for gastrointestinal motility: potential for prokinetic treatment and prevention in elderly.The EPMA journal · 2015Article
- Acetylcholine serves as a derepressor in Loperamide-induced Opioid-Induced Bowel Dysfunction (OIBD) in zebrafish.Scientific reports · 2014Article
- Expression and function of NIK- and IKK2-binding protein (NIBP) in mouse enteric nervous system.Neurogastroenterology and motility · 2014Article
- The 5-hydroxytryptamine 4 Receptor Agonist-induced Actions and Enteric Neurogenesis in the Gut.Journal of neurogastroenterology and motility · 2014Review
- GDNF and endothelin 3 regulate migration of enteric neural crest-derived cells via protein kinase A and Rac1.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Transplanted progenitors generate functional enteric neurons in the postnatal colon.The Journal of clinical investigation · 2013Article
- Differences in the development of autogenous nerves between the upper and lower urinary tract.Experimental and therapeutic medicine · 2013Article
- Development and developmental disorders of the enteric nervous system.Nature reviews. Gastroenterology & hepatology · 2013Review
- Effects of oxaliplatin on mouse myenteric neurons and colonic motility.Frontiers in neuroscience · 2013Article
- Alternative splicing results in RET isoforms with distinct trafficking properties.Molecular biology of the cell · 2012Article
- Trans-mesenteric neural crest cells are the principal source of the colonic enteric nervous system.Nature neuroscience · 2012Article
- The microenvironment in the Hirschsprung's disease gut supports myenteric plexus growth.International journal of colorectal disease · 2012Article
- Immunophenotypic characterization of enteric neural crest cells in the developing avian colorectum.Developmental dynamics : an official publication of the American Association of Anatomists · 2012Article
- Smooth muscle proteins from Hirschsprung's disease facilitates stem cell differentiation.Pediatric surgery international · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The enteric nervous system (ENS) is the largest and most complicated subdivision of the peripheral nervous system. Its action is necessary to regulate many of the functions of the gastrointestinal tract including its motility. Whilst the ENS has been studied extensively by developmental biologists, neuroscientists and physiologists for several decades it has only been since the early 1990s that the molecular and genetic basis of ENS development has begun to emerge. Central to this understanding has been the use of genetic model organisms. In this article, we will discuss recent advances that have been achieved using both mouse and zebrafish model genetic systems that have led to new insights into ENS development and the genetic basis of Hirschsprung's disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.