Evidence map›Paper›PMID 19214613›Full record

ArticleMedical & biological engineering & computing2009

Multi-objective blood glucose control for type 1 diabetes.

Pinky Dua, Francis J Doyle, Efstratios N Pistikopoulos

Abstract read
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Article in Medical & biological engineering & computing, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Blood glucose concentration prediction based on VMD-KELM-AdaBoost.Medical & biological engineering & computing · 2021
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Periodic zone-MPC with asymmetric costs for outpatient-ready safety of an artificial pancreas to treat type 1 diabetesAutomatica : the journal of IFAC, the International Federation of Automatic Control · 2016
    Article
  8. Article
  9. Article
  10. Designing an artificial pancreas architecture: the AP@home experience.Medical & biological engineering & computing · 2015
    Article
  11. MPC Design for Rapid Pump-Attenuation and Expedited Hyperglycemia Response to Treat T1DM with an Artificial Pancreas.Proceedings of the ... American Control Conference. American Control Conference · 2014
    Article
  12. Article
  13. Review
  14. Modelling and multi-parametric control for delivery of anaesthetic agents.Medical & biological engineering & computing · 2010
    Article
  15. Quest for the artificial pancreas: combining technology with treatment.IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pinky DuaDepartment of Chemical Engineering, Centre for Process Systems Engineering, Imperial College London, South Kensington Campus, London SW72AZ, UK. Pinky.2.dua@gsk.com
Francis J Doyle
Efstratios N Pistikopoulos

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For people with type 1 diabetes, automatic controllers aim to maintain the blood glucose concentration within the desired range of 60-120 mg/dL by infusing the appropriate amount of insulin in the presence of meal and exercise disturbances. Blood glucose concentration outside the desired range can be harmful to an individual's health but concentration below 60 mg/dL, a state known as hypoglycemia, is considered to be more harmful than the concentration above 120 mg/dL, a state known as hyperglycemia. In this paper, two techniques to address this issue within a multi-parametric model based control framework are presented. The first technique introduces asymmetry into the objective function to penalize the deviation towards hypoglycemia more than the deviation towards hyperglycemia. The second technique is based upon placing higher priority on satisfaction of constraints on hypoglycemia than on satisfaction of constraints on hyperglycemia. The performance of both the control techniques is analyzed and compared in the presence of disturbances.

Indexed as

Models, BiologicalBlood GlucoseDiabetes Mellitus, Type 1Drug Administration ScheduleDrug Delivery SystemsHumansHyperglycemiaHypoglycemiaHypoglycemic AgentsInsulinBlood GlucoseHypoglycemic AgentsInsulin

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.