ArticleJournal of clinical microbiology2009
Presence and molecular epidemiology of virulence factors in methicillin-resistant Staphylococcus aureus strains colonizing and infecting soldiers.
Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- The association between community-associated Staphylococcus aureus colonization and disease: a meta-analysis.BMC infectious diseases · 2018Pooled it
- Safety and immunogenicity of a recombinant Staphylococcus aureus α-toxoid and a recombinant Panton-Valentine leukocidin subunit, in healthy adults.Human vaccines & immunotherapeutics · 2017Trial
- Molecular epidemiology of Staphylococcus aureus in households of children with community-associated S aureus skin and soft tissue infections.The Journal of pediatrics · 2014Trial
- Chlorhexidine gluconate reduces transmission of methicillin-resistant Staphylococcus aureus USA300 among Marine recruits.Infection control and hospital epidemiology · 2012Trial
- Selective Targeting and Enhanced Photodynamic Inactivation of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2025Article
- Contribution of Arginine Catabolic Mobile Element and Copper and Mercury Resistance Element in Methicillin-ResistantThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022Review
- Infective endocarditis: Role of molecular techniques in early diagnosis.Saudi journal of biological sciences · 2021Review
- Colonization withMicrobial genomics · 2021Article
- Risk of Skin and Soft Tissue Infections among Children Found to beThe western journal of emergency medicine · 2017Article
- Lack of doxycycline antimalarial prophylaxis impact on Staphylococcus aureus tetracycline resistance.Diagnostic microbiology and infectious disease · 2016Observational
- Methicillin-susceptible Staphylococcus aureus skin infections among military conscripts undergoing basic training in Bangkok, Thailand, in 2014.BMC research notes · 2016Article
- Prevalence of Nasal colonization withTropical diseases, travel medicine and vaccines · 2016Article
- Bacterial Etiology and Risk Factors Associated with Cellulitis and Purulent Skin Abscesses in Military Trainees.PloS one · 2016Article
- Neglect of skin wounds and the risk of becoming a Staphylococcus aureus nasal carrier: a cohort study.BMC public health · 2015Article
- Molecular characterization of a catalase-negative methicillin-susceptible Staphylococcus aureus subsp. aureus strain collected from a patient with cutaneous abscess.Journal of clinical microbiology · 2014Article
- A comparative analysis of community acquired and hospital acquired methicillin resistant Staphylococcus aureus.Journal of clinical and diagnostic research : JCDR · 2013Article
- Current concepts on the virulence mechanisms of meticillin-resistant Staphylococcus aureus.Journal of medical microbiology · 2012Review
- Virulence strategies of the dominant USA300 lineage of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA).FEMS immunology and medical microbiology · 2012Review
- Characterization of a novel arginine catabolic mobile element (ACME) and staphylococcal chromosomal cassette mec composite island with significant homology to Staphylococcus epidermidis ACME type II in methicillin-resistant Staphylococcus aureus genotype ST22-MRSA-IV.Antimicrobial agents and chemotherapy · 2011Article
- Molecular distinctions exist between community-associated methicillin-resistant Staphylococcus aureus colonization and disease-associated isolates in children.The Pediatric infectious disease journal · 2011Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as an important cause of skin and soft-tissue infections (SSTI). The understanding of the molecular epidemiology and virulence of MRSA continues to expand. From January 2005 to December 2005, we screened soldiers for MRSA nasal colonization, administered a demographic questionnaire, and monitored them prospectively for SSTI. All MRSA isolates underwent molecular analysis, which included pulsed-filed gel electrophoresis (PFGE) and PCR for Panton-Valentine leukocidin (PVL), the arginine catabolic mobile element (ACME), and the staphylococcal cassette chromosome mec (SCCmec). Of the 3,447 soldiers screened, 134 (3.9%) had MRSA colonization. Of the 3,066 (89%) who completed the study, 39 developed culture-confirmed MRSA abscesses. Clone USA300 represented 53% of colonizing isolates but was responsible for 97% of the abscesses (P < 0.001). Unlike colonizing isolates, isolates positive for USA300, PVL, ACME, and type IV SCCmec were significantly associated with MRSA abscess isolates. As determined by multivariate analysis, risk factors for MRSA colonization were a history of SSTI and a history of hospitalization. Although various MRSA strains may colonize soldiers, USA300 is the most virulent when evaluated prospectively, and PVL, ACME, and type IV SCCmec are associated with these abscesses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.