ArticleFrontiers in systems neuroscience2009
Nerve-Injury Induced Changes to GluR1 and GluR2/3 Sub-unit Expression in Area 3b of Adult Squirrel Monkeys: Developmental Recapitulation?
Article in Frontiers in systems neuroscience, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Adult neuroplasticity employs developmental mechanisms.Frontiers in systems neuroscience · 2022Pooled it
- Cortical Reorganization after Limb Loss: Bridging the Gap between Basic Science and Clinical Recovery.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Differences in AMPA and GABAA/B receptor subunit expression between the chronically reorganized cortex and brainstem of adult squirrel monkeys.Brain research · 2015Article
- Reconciling homeostatic and use-dependent plasticity in the context of somatosensory deprivation.Neural plasticity · 2015Review
- Reorganization of retinotopic maps after occipital lobe infarction.Journal of cognitive neuroscience · 2014Article
- AMPA and GABA(A/B) receptor subunit expression in the cuneate nucleus of adult squirrel monkeys during peripheral nerve regeneration.Neuroscience letters · 2014Article
- Functional signature of recovering cortex: dissociation of local field potentials and spiking activity in somatosensory cortices of spinal cord injured monkeys.Experimental neurology · 2013Article
- AMPA and GABA(A/B) receptor subunit expression in the cortex of adult squirrel monkeys during peripheral nerve regeneration.Brain research · 2013Article
- Dynamic reorganization of digit representations in somatosensory cortex of nonhuman primates after spinal cord injury.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- AMPA receptor subunit expression in the cuneate nucleus of adult squirrel monkeys after peripheral nerve injury.Neuroscience letters · 2012Article
- Recovery of neurofilament following early monocular deprivation.Frontiers in systems neuroscience · 2012Article
- Optogenetic-guided cortical plasticity after nerve injury.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Natural restoration of critical period plasticity in the juvenile and adult primary auditory cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The primate somatosensory system provides an excellent model system with which to investigate adult neural plasticity. Here, we report immunohistochemical staining data for the GluR1 and GluR2/3 AMPA receptors subunits in somatosensory area 3b 1 week after median nerve compression in adult squirrel monkeys. We find transcortical increases in the staining intensity of GluR1 AMPAR subunits and transcortical decreases in GluR2/3 AMPAR subunits. This pattern of change in the staining intensity of these subunits differs from the changes one would expect if the deprived cortical neurons were undergoing homeostatic synaptic scaling, or from ones that would follow N-methyl-d-aspartate (NMDA) receptor-mediated long-term potentiation. Indeed, this pattern of change appears to recapitulate proportions that exist early in development as if the deprived cortex has reverted to an immature state. We suggest that this state represents yet another stage of peripheral nerve injury-induced reorganization in adult primate somatosensory cortex, and may well be essential for subsequent NMDA receptor-mediated plasticity.
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Registered trials
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