Evidence map›Paper›PMID 19208991›Full record

ArticleCaries research2009

Biomechanical perspective on the remineralization of dentin.

L E Bertassoni, S Habelitz, J H Kinney, S J Marshall, G W Marshall

Abstract readEvaluation Study
In one paragraph

Article in Caries research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Research progress of biomimetic materials in oral medicine.Journal of biological engineering · 2023
    Review
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

L E BertassoniDivision of Biomaterials and Bioengineering, Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, San Francisco, CA 94143-0758, USA.
S Habelitz
J H Kinney
S J Marshall
G W Marshall

Funding

DENTIN STRUCTURE, DEMINERALIZATION AND REMINERALIZATIONR01DE016849 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GOWER, LAURIE B, HABELITZ, STEFAN FRIEDRICH · 2006 to 2016
$5.1M
NIDCR NIH HHS R01 DE016849NIDCR NIH HHS R01DE16849
6 · The paper itself

Abstract

The objective of this article is to critically evaluate the methods that are used to assess outcomes of remineralization of dentin. Currently, the most used assessment methods fall either into quantitative analysis of the mineral content of the remineralized structures or dry measurements of their mechanical properties. Properties obtained from the dehydrated organic dentin matrix may not reflect the true mechanical behavior of the remineralized tissue under physiological and hydrated conditions. Here we seek to clarify the biomechanical aspects of remineralization of dentin, pointing out the effects of hydration and dehydration on the mechanical properties of treated tissues. We also emphasize that a more appropriate endpoint to evaluate the effectiveness of remineralization in dentin should be associated with the recovery of the mechanical properties of the hydrated tissue, which is presumed to correlate well with its overall functionality.

Indexed as

Tooth RemineralizationBiomechanical PhenomenaDental Stress AnalysisDentinDesiccationElasticityFibrillar CollagensHardness TestsHumansMicroradiographyMicroscopy, Electron, TransmissionModels, ChemicalOutcome Assessment, Health CareSpectrum AnalysisThermogravimetryWaterFibrillar CollagensWater

Identifiers

PMID19208991
PMCPMC2698028

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.