Evidence map›Paper›PMID 19208250›Full record

ArticleGenome biology2009

EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data.

Christoph Bock, Konstantin Halachev, Joachim Büch, Thomas Lengauer

Abstract read
In one paragraph

Article in Genome biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  16. Analysing and interpreting DNA methylation data.Nature reviews. Genetics · 2012
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christoph BockMax-Planck-Institut für Informatik, Campus E1.4, 66123 Saarbrücken, Germany. cbock@mpi-inf.mpg.de
Konstantin Halachev
Joachim Büch
Thomas Lengauer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The EpiGRAPH web service http://epigraph.mpi-inf.mpg.de/ enables biologists to uncover hidden associations in vertebrate genome and epigenome datasets. Users can upload sets of genomic regions and EpiGRAPH will test multiple attributes (including DNA sequence, chromatin structure, epigenetic modifications and evolutionary conservation) for enrichment or depletion among these regions. Furthermore, EpiGRAPH learns to predictively identify similar genomic regions. This paper demonstrates EpiGRAPH's practical utility in a case study on monoallelic gene expression and describes its novel approach to reproducible bioinformatic analysis.

Indexed as

Epigenesis, GeneticSoftwareAnimalsComputational BiologyDatabases, Nucleic AcidGenomicsUser-Computer InterfaceVertebrates

Identifiers

PMID19208250
PMCPMC2688269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.