ArticleDNA and cell biology2009
Resident microbiota of the gypsy moth midgut harbors antibiotic resistance determinants.
Article in DNA and cell biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 92 citations in OpenAlex.
- ResFinderFG v2.0: a database of antibiotic resistance genes obtained by functional metagenomics.Nucleic acids research · 2023Article
- Screening of Spore-Forming Bacteria with Probiotic Potential in Pristine Algerian Caves.Microbiology spectrum · 2022Article
- Interkingdom Gut Microbiome and Resistome of the CockroachmSystems · 2021Article
- Insects, Rodents, and Pets as Reservoirs, Vectors, and Sentinels of Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2021Review
- Antibiotic resistance: Time of synthesis in a post-genomic age.Computational and structural biotechnology journal · 2021Review
- Diverse and abundant resistome in terrestrial and aquatic vertebrates revealed by transcriptional analysis.Scientific reports · 2020Article
- Antimicrobial resistance and genetic relationships of enterococci from siblings and non-siblingsPeerJ · 2020Article
- Household cockroaches carry CTX-M-15-, OXA-48- and NDM-1-producing enterobacteria, and share beta-lactam resistance determinants with humans.BMC microbiology · 2019Article
- Oxytetracycline reduces the diversity of tetracycline-resistance genes in the Galleria mellonella gut microbiome.BMC microbiology · 2018Article
- Comparative mangrove metagenome reveals global prevalence of heavy metals and antibiotic resistome across different ecosystems.Scientific reports · 2018Article
- Antibiotic-resistant bacteria in the guts of insects feeding on plants: prospects for discovering plant-derived antibiotics.BMC microbiology · 2017Article
- New Insights into the Microbiota of Moth Pests.International journal of molecular sciences · 2017Review
- Distribution and Classification of Serine β-Lactamases in Brazilian Hospital Sewage and Other Environmental Metagenomes Deposited in Public Databases.Frontiers in microbiology · 2016Article
- Insights into resistome and stress responses genes in Bubalus bubalis rumen through metagenomic analysis.Molecular biology reports · 2014Article
- Insects represent a link between food animal farms and the urban environment for antibiotic resistance traits.Applied and environmental microbiology · 2014Review
- Insect gut microbiome - An unexploited reserve for biotechnological application.Asian Pacific journal of tropical biomedicine · 2014Review
- Cloacibacillus porcorum sp. nov., a mucin-degrading bacterium from the swine intestinal tract and emended description of the genus Cloacibacillus.International journal of systematic and evolutionary microbiology · 2013Article
- Microbe-dependent and nonspecific effects of procedures to eliminate the resident microbiota from Drosophila melanogaster.Applied and environmental microbiology · 2013Article
- Novel resistance functions uncovered using functional metagenomic investigations of resistance reservoirs.Frontiers in microbiology · 2013Article
- Assessing the effectiveness of functional genetic screens for the identification of bioactive metabolites.Marine drugs · 2012Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
Little is known about the significance of insects as environmental reservoirs of antibiotic-resistant bacteria. We characterized the antibiotic resistome of the microbial community in gypsy moth larval midguts by applying functional metagenomics to cultured isolates. The minimum inhibitory concentrations of 12 antibiotics were determined for 44 cultured isolates, and antibiotic resistance genes were selected from metagenomic libraries derived from DNA extracted from a pool of the isolates. Six unique clones were identified. Two were highly resistant to penicillin-type beta-lactams, two were moderately resistant to erythromycin, and two were moderately resistant to a range of antibiotics, including erythromycin, carbenicillin, and chloramphenicol. Sequence analysis predicted that the active genes encoded efflux pumps, a transcriptional activator of efflux pump protein expression, and an extended-spectrum class A beta-lactamase. Insect guts are a reservoir of antibiotic resistance genes with the potential for dissemination.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.