Evidence map›Paper›PMID 19205736›Full record

ArticleJournal of cancer research and clinical oncology2009

Medical history and risk of lymphoma: results of a European case-control study (EPILYMPH).

Nikolaus Becker, Joan Fortuny, Tomas Alvaro, Alexandra Nieters, Marc Maynadié, Lenka Foretova, Anthony Staines, Paul Brennan, Paolo Boffetta, Pier Luigi Cocco and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

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  5. Association of risk of non-Hodgkin's lymphoma with hepatitis B virus infection: a meta-analysis.International journal of clinical and experimental medicine · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 6 countries.

Nikolaus BeckerDivision of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany. n.becker@dkfz.de
Joan Fortuny
Tomas Alvaro
Alexandra Nieters
Marc Maynadié
Lenka Foretova
Anthony Staines
Paul Brennan
Paolo Boffetta
Pier Luigi Cocco
Silvia de Sanjose
Centre International de Recherche sur le Cancer · FRInstitut Català d'Ornitologia · ESDublin City University · IEGerman Cancer Research Center · DEHeidelberg University · DEInstitut Català d'Oncologia · ESMasaryk Memorial Cancer Institute · CZUniversité de Bourgogne · FRUniversity of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLymphomas are a heterogeneous group of immune-cell malignancies. Immunology-related conditions are among the few factors for which consistent evidence exists relating them to lymphoma risk. MATERIALS AND

methodsWe used the data from the European case-control study Epilymph on 2,362 lymphoma cases and 2,458 controls to investigate associations between a medical history of infectious and non-infectious diseases with overall and subentity-specific lymphoma risk.

resultsAs key results, we observed an increased odds ratio (OR) for self-reported infections with hepatitis B virus (HBV, OR = 1.91, 95% CL = 1.24-2.94) and a null result for rheumatoid arthritis. Additionally, we found an increased OR for infectious mononucleosis (OR = 1.68, 95% CL = 1.14-2.48), an inverse association to frequency of sickness in childhood (OR = 0.68, 95% CL = 0.55-0.84), and-as casual finding-an increased OR with acetaminophen intake (OR = 2.29, 95% CL = 1.49-3.51).

conclusionOur results are consistent with the current knowledge about the association with mononucleosis as indicator of Epstein-Barr-virus infection, suggest serological study of the association to HBV infection and do not support the view of a positive association between rheumatoid arthritis and lymphoma risk.

Indexed as

AdultAgedArthritis, RheumatoidCase-Control StudiesEpstein-Barr Virus InfectionsFemaleHepatitis BHumansInfectious MononucleosisLymphomaMaleMiddle AgedOdds RatioRisk Factors

Identifiers

PMID19205736
PMCPMC12160207
OpenAlexW2057672325

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.