ArticleEuropean journal of clinical pharmacology2009
SFINX-a drug-drug interaction database designed for clinical decision support systems.
Article in European journal of clinical pharmacology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
85 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Gaps in the detection of drug-drug interactions between antipsychotic and cardiometabolic medications: a multisource analysis.BMC medicine · 2025Pooled it
- Intervention of pharmacist included in multidisciplinary team to reduce adverse drug event: a qualitative systematic review.BMC health services research · 2023Pooled it
- Information needs for making clinical recommendations about potential drug-drug interactions: a synthesis of literature review and interviews.BMC medical informatics and decision making · 2017Pooled it
- Drug-drug interaction software in clinical practice: a systematic review.European journal of clinical pharmacology · 2015Pooled it
- Effectiveness of a Hospital-Based Computerized Decision Support System on Clinician Recommendations and Patient Outcomes: A Randomized Clinical Trial.JAMA network open · 2019Trial
- Enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trial.BMC geriatrics · 2019Trial
- Coordinating resources for prospective medication risk management of older home care clients in primary care: procedure development and RCT study design for demonstrating its effectiveness.BMC geriatrics · 2018Trial
- Implementing an evidence-based computerized decision support system to improve patient care in a general hospital: the CODES study protocol for a randomized controlled trial.Implementation science : IS · 2016Trial
- Trial
- Effectiveness of the Prospective Prescription Review System in Reducing Irrational Prescriptions at a Tertiary Specialty Hospital: Retrospective Cohort Study.JMIR formative research · 2026Article
- Dual channel drug-drug interactions extraction based on cross attention.BMC bioinformatics · 2026Article
- Machine Learning-Based Prediction of Drug-Induced QTc Changes in a Large Finnish Biobank Cohort.Clinical and translational science · 2026Article
- Machine learning models for drug-drug interaction prediction from computational discovery to clinical application.NPJ digital medicine · 2026Review
- Questions in Healthcare Specifically Related to the Discipline of Pharmacy: A Descriptive Analysis of Queries to Drug Information Centres in Sweden.Basic & clinical pharmacology & toxicology · 2025Article
- Exploring the need for a clinical decision support system for deprescribing - A qualitative interview study.Exploratory research in clinical and social pharmacy · 2025Article
- Pharmacotherapeutic actions related to drug interaction alerts - a questionnaire study among Swedish hospital interns and residents in family medicine.European journal of clinical pharmacology · 2025Article
- Potential Adverse Drug Events Identified with Decision Support Algorithms from Janusmed Risk Profile-A Retrospective Population-Based Study in a Swedish Region.Pharmacy (Basel, Switzerland) · 2024Article
- Apixaban plasma concentrations in patients with obesity.European journal of clinical pharmacology · 2024Article
- Collaborative medication reviews in community pharmacies-Drug-related problems and the process of communicating them with physicians: A retrospective validation study.Health science reports · 2024Article
- Drug-Drug Interactions in Patients with Acute Respiratory Distress Syndrome.Pharmaceutics · 2024Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim was to develop a drug-drug interaction database (SFINX) to be integrated into decision support systems or to be used in website solutions for clinical evaluation of interactions.
methodsKey elements such as substance properties and names, drug formulations, text structures and references were defined before development of the database. Standard operating procedures for literature searches, text writing rules and a classification system for clinical relevance and documentation level were determined. ATC codes, CAS numbers and country-specific codes for substances were identified and quality assured to ensure safe integration of SFINX into other data systems. Much effort was put into giving short and practical advice regarding clinically relevant drug-drug interactions.
resultsSFINX includes over 8,000 interaction pairs and is integrated into Swedish and Finnish computerised decision support systems. Over 31,000 physicians and pharmacists are receiving interaction alerts through SFINX. User feedback is collected for continuous improvement of the content.
conclusionSFINX is a potentially valuable tool delivering instant information on drug interactions during prescribing and dispensing.
Indexed as
Identifiers
19205683What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.