ArticleGenetics2009
Duplication, selection and gene conversion in a Drosophila mojavensis female reproductive protein family.
Article in Genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 39 citations in OpenAlex.
- Correlated Gene Copy Number Changes in a Seminal Fluid Protein Network inbioRxiv : the preprint server for biology · 2025Article
- Regional specialization, polyploidy, and seminal fluid transcripts in theProceedings of the National Academy of Sciences of the United States of America · 2024Article
- The roles of gene duplications in the dynamics of evolutionary conflicts.Proceedings. Biological sciences · 2024Review
- The seminal odorant binding protein Obp56g is required for mating plug formation and male fertility ineLife · 2023Article
- The Importance of Gene Duplication and Domain Repeat Expansion for the Function and Evolution of Fertilization Proteins.Frontiers in cell and developmental biology · 2022Review
- The evolution of duplicate gene expression in mammalian organs.Genome research · 2017Article
- Effects of temperature on transcriptome and cuticular hydrocarbon expression in ecologically differentiated populations of desertEcology and evolution · 2017Article
- Deep RNA-Seq profile reveals biodiversity, plant-microbe interactions and a large family of NBS-LRR resistance genes in walnut (Juglans regia) tissues.AMB Express · 2016Article
- Article
- The "life histories" of genes.Journal of molecular evolution · 2015Article
- Adaptive evolution of genes involved in the regulation of germline stem cells in Drosophila melanogaster and D. simulans.G3 (Bethesda, Md.) · 2015Article
- Genomics of ecological adaptation in cactophilic Drosophila.Genome biology and evolution · 2014Article
- Molecular characterization and evolution of a gene family encoding both female- and male-specific reproductive proteins in Drosophila.Molecular biology and evolution · 2014Article
- Using RNA sequencing to characterize female reproductive genes between Z and E Strains of European Corn Borer moth (Ostrinia nubilalis).BMC genomics · 2014Article
- Gene duplication as a mechanism of genomic adaptation to a changing environment.Proceedings. Biological sciences · 2012Review
- Widespread polymorphism in the positions of stop codons in Drosophila melanogaster.Genome biology and evolution · 2012Article
- Temporally variable selection on proteolysis-related reproductive tract proteins in Drosophila.Molecular biology and evolution · 2012Article
- Sperm-storage defects and live birth in Drosophila females lacking spermathecal secretory cells.PLoS biology · 2011Article
- Identification of ejaculated proteins in the house mouse (Mus domesticus) via isotopic labeling.BMC genomics · 2011Article
- Postmating transcriptional changes in reproductive tracts of con- and heterospecifically mated Drosophila mojavensis females.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein components of the Drosophila male ejaculate, several of which evolve rapidly, are critical modulators of reproductive success. Recent studies of female reproductive tract proteins indicate they also are extremely divergent between species, suggesting that reproductive molecules may coevolve between the sexes. Our current understanding of intersexual coevolution, however, is severely limited by the paucity of genetic and evolutionary studies on the female molecules involved. Physiological evidence of ejaculate-female coadaptation, paired with a promiscuous mating system, makes Drosophila mojavensis an exciting model system in which to study the evolution of reproductive proteins. Here we explore the evolutionary dynamics of a five-paralog gene family of female reproductive proteases within populations of D. mojavensis and throughout the repleta species group. We show that the proteins have experienced ongoing gene duplication and adaptive evolution and further exhibit dynamic patterns of pseudogenation, copy number variation, gene conversion, and selection within geographically isolated populations of D. mojavensis. The integration of these patterns in a single gene family has never before been documented in a reproductive protein.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.