Evidence map›Paper›PMID 19204371›Full record

ArticleAmerican journal of Alzheimer's disease and other dementias2010

EEG markers discriminate among different subgroup of patients with mild cognitive impairment.

D V Moretti, M Pievani, C Geroldi, G Binetti, O Zanetti, P M Rossini, G B Frisoni

Abstract read
In one paragraph

Article in American journal of Alzheimer's disease and other dementias, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

D V MorettiNeurophysiology, IRCCS S. Giovanni di Dio Fatebenefratelli, Brescia, Italy. davide.moretti@afar.it
M Pievani
C Geroldi
G Binetti
O Zanetti
P M Rossini
G B Frisoni

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim of the study is to discriminate among participants with mild cognitive impairment through electroencephalography brain rhythms. A total of 79 participants with MCI were classified into 4 subgroups based on the beginning of memory complaints up to the time of first visit. All participants underwent electroencephalography recording, magnetic resonance imaging, apolipoprotein E characterization, and volumetric morphometry estimation of hippocampal region. Electroencephalography markers show 2 distinct patterns: (1) increase of theta/ delta power ratio and highest value of alpha2 band power in the group with shorter duration of disease, the greater right-left hippocampal volume difference and worst memory performance; (2) the highest value of alpha3 band power and the highest alpha3/alpha2 power ratio in the group with the lesser total hippocampal volume but preserved memory performance. Apolipoprotein E4 is linked to a major risk of early beginning of disease. Electroencephalography markers allow a mean correct percentage of correct classification up to 89%.

Indexed as

ElectroencephalographyAgedAged, 80 and overAlpha RhythmAlzheimer DiseaseApolipoproteins ECognition DisordersFemaleHumansMaleNeuropsychological TestsPrevalenceSeverity of Illness IndexApolipoproteins E

Identifiers

PMID19204371
PMCPMC10845572

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.