ReviewTransplantation2009
Hematopoietic cell transplantation for tolerance induction: animal models to clinical trials.
Review in Transplantation, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 64 citations in OpenAlex.
- T cell-mediated immune responses in xenotransplantation: mechanisms and therapeutic strategies.Frontiers in immunology · 2026Review
- Progress in xenotransplantation: overcoming immune barriers.Nature reviews. Nephrology · 2022Review
- Review
- Progress in Liver Transplant Tolerance and Tolerance-Inducing Cellular Therapies.Frontiers in immunology · 2020Review
- Enhancement of Antigen Presentation by Deletion of Viral Immune Evasion Genes Prevents Lethal Cytomegalovirus Disease in Minor Histocompatibility Antigen-Mismatched Hematopoietic Cell Transplantation.Frontiers in cellular and infection microbiology · 2020Article
- Transplanting organs from pigs to humans.Science immunology · 2019Review
- Placental Stem Cells from Domestic Animals: Translational Potential and Clinical Relevance.Cell transplantation · 2018Article
- Hematopoietic stem cells and solid organ transplantation.Transplantation reviews (Orlando, Fla.) · 2016Review
- Preconditioning allows engraftment of mouse and human embryonic lung cells, enabling lung repair in mice.Nature medicine · 2015Article
- Myeloid-lymphoid ontogeny in the rhesus monkey (Macaca mulatta).Anatomical record (Hoboken, N.J. : 2007) · 2014Article
- CD4+ T cell-depleted lymphocyte infusion impairs neither the recovery of recipient thymus nor the development of transplanted thymus.Journal of immunology (Baltimore, Md. : 1950) · 2013Article
- Chimerism-based experimental models for tolerance induction in vascularized composite allografts: Cleveland clinic research experience.Clinical & developmental immunology · 2013Article
- Center for fetal monkey gene transfer for heart, lung, and blood diseases: an NHLBI resource for the gene therapy community.Human gene therapy · 2012Review
- CD4(+)Foxp3(+) regulatory T cell therapy in transplantation.Journal of molecular cell biology · 2012Review
- Combination of intra-bone marrow-bone marrow transplantation and subcutaneous donor splenocyte injection diminishes risk of graft-versus-host disease and enhances survival rate.Stem cells and development · 2011Article
- Clinical transplantation tolerance.Seminars in immunopathology · 2011Review
- Clinical operational tolerance after renal transplantation: current status and future challenges.Annals of surgery · 2010Review
- Review
- Allogeneic haematopoietic stem cell transplantation: individualized stem cell and immune therapy of cancer.Nature reviews. Cancer · 2010Review
- Point: steady progress and current challenges in clinical islet transplantation.Diabetes care · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The induction of donor-specific immune tolerance is the "holy grail" of transplantation, as it would avoid the toxicities of chronic immunosuppressive therapies while preventing acute and chronic graft rejection. A large number of approaches to tolerance induction have been described in the experimental literature, but only hematopoietic cell transplantation has shown preliminary success for intentional tolerance induction in pilot clinical trials. This review summarizes the conditions that allow progress to be made in moving strategies for tolerance induction from the bench to the bedside and discuss the mechanisms by which tolerance may be achieved through hematopoietic cell transplantation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.