ArticleInternational journal of experimental pathology2009
Identification of monoclinic calcium pyrophosphate dihydrate and hydroxyapatite in human sclera using Raman microspectroscopy.
Article in International journal of experimental pathology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Calcium Pyrophosphate Crystal Formation and Deposition: Where Do we Stand and What Does the Future hold?Current rheumatology reports · 2024Review
- Sociodemographic Factors and Comorbidities Including Hyperparathyroidism Are Associated With an Increased Risk of Band Keratopathy: A Population-Based Study in Taiwan.Frontiers in endocrinology · 2022Article
- Synthesis and characterization of antibacterial drug loaded β-tricalcium phosphate powders for bone engineering applications.Journal of materials science. Materials in medicine · 2020Article
- Effect of reaction solvent on hydroxyapatite synthesis in sol-gel process.Royal Society open science · 2017Article
- Presence of pyrophosphate in bone from an atypical femoral fracture site: A case report.Bone reports · 2017Article
- Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification.Cell stem cell · 2017Article
- Role of "osteogenic" cardiac fibroblasts in pathological heart calcification.Stem cell investigation · 2017Article
- Is there a relationship between solubility and resorbability of different calcium phosphate phases in vitro?Biochimica et biophysica acta · 2016Article
- A Point-of-Care Raman Spectroscopy-Based Device for the Diagnosis of Gout and Pseudogout: Comparison With the Clinical Standard Microscopy.Arthritis & rheumatology (Hoboken, N.J.) · 2016Article
- Prophylactic removal and microbiological evaluation of calcified plaques after pterygium surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2016Article
- Spectral diagnosis and analysis of a superior vesical artery calcification.Urological research · 2009Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Raman microspectroscopy was first used to determine the composition of a calcified plaque located at the pterygium-excision site of a 51-year-old female patient's left nasal sclera after surgery. It was unexpectedly found that the Raman spectrum of the calcified sample at 1149, 1108, 1049, 756, 517, 376 and 352/cm was similar to the Raman spectrum of monoclinic form of calcium pyrophosphate dihydrate (CPPD) crystal, but differed from the Raman spectrum of triclinic form of CPPD. An additional peak at 958/cm was also observed in the Raman spectrum of the calcified plaque, which was identical to the characteristic peak at 958/cm of hydroxyapatite (HA). This is the first study to report the spectral biodiagnosis of both monoclinic CPPD and HA co-deposited in the calcified plaque of a patient with sclera dystrophic calcification using Raman microspectroscopy.
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