Evidence map›Paper›PMID 19199815›Full record

ArticleJournal of natural products2009

Okundoperoxide, a bicyclic cyclofarnesylsesquiterpene endoperoxide from Scleria striatinux with antiplasmodial activity.

Simon M N Efange, Reto Brun, Sergio Wittlin, Joseph D Connolly, Thomas R Hoye, Thomas McAkam, Felix L Makolo, James A Mbah, Dorian P Nelson, Kennedy D Nyongbela and 1 more

Abstract read
In one paragraph

Article in Journal of natural products, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Antimalarial Natural Products.Progress in the chemistry of organic natural products · 2022
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Simon M N EfangeDepartment of Chemistry, University of Buea, PO Box 63, Buea, Southwest Province, Cameroon. smnefange@yahoo.com
Reto Brun
Sergio Wittlin
Joseph D Connolly
Thomas R Hoye
Thomas McAkam
Felix L Makolo
James A Mbah
Dorian P Nelson
Kennedy D Nyongbela
Clare K Wirmum

Funding

Synthesis Strategies for Bioactive Natural ProductsR01GM065597 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI HOYE, THOMAS R. · 2002 to 2016
$3.1M
FIC NIH HHS TW00327NIGMS NIH HHS GM-65597NIGMS NIH HHS R01 GM065597
6 · The paper itself

Abstract

Okundoperoxide (1) was isolated by bioassay-guided fractionation of extracts from Scleria striatinux (syn. S. striatonux). The compound contains a cyclic endoperoxide structural moiety and possesses moderate antimalarial activity.

Indexed as

AntimalarialsChloroquineCyperaceaeDrug ResistanceMolecular StructureNuclear Magnetic Resonance, BiomolecularPlant RootsPlants, MedicinalPlasmodium falciparumSesquiterpenesStereoisomerismAntimalarialsChloroquineokundoperoxideSesquiterpenes

Identifiers

PMID19199815
PMCPMC2765531

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.