Evidence map›Paper›PMID 19199706›Full record

ArticleJournal of proteome research2009

Analysis of neuropeptide expression and localization in adult drosophila melanogaster central nervous system by affinity cell-capture mass spectrometry.

Joanne Y Yew, Yun Wang, Natasha Barteneva, Sergei Dikler, Kimberly K Kutz-Naber, Lingjun Li, Edward A Kravitz

Erratum issuedAbstract read
In one paragraph

Article in Journal of proteome research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Identification and In Vivo Characterisation of Cardioactive Peptides inInternational journal of molecular sciences · 2018
    Article
  8. Neuropeptide Mapping of Dimmed Cells of Adult Drosophila Brain.Journal of the American Society for Mass Spectrometry · 2018
    Article
  9. eLife · 2016
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Small-volume analysis of cell-cell signaling molecules in the brain.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014
    Review
  16. Article
  17. Article
  18. Article
  19. Chemical analysis of single cells.Analytical chemistry · 2011
    Review
  20. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

7 authors.

Joanne Y YewDepartment of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA. joanne_yew@hms.harvard.edu
Yun Wang
Natasha Barteneva
Sergei Dikler
Kimberly K Kutz-Naber
Lingjun Li
Edward A Kravitz

Funding

Mass Spectrometric Studies of Neuropeptides in FeedingR01DK071801 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI LINGJUN LI · 2006 to 2026
$6.7M
Mutant Studies of Aggression in DrosophilaR01GM067645 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KRAVITZ, EDWARD A · 2003 to 2011
$3.2M
Hormonal Modulation of Aggression in DrosophilaR01GM074675 · NIGMS · HARVARD MEDICAL SCHOOL · PI KRAVITZ, EDWARD A · 2006 to 2014
$2.6M
Mass Spectrometric Studies of Neuropeptides in FeedingR56DK071801 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2011 to 2011
$216k
Neuropeptide Modulation of AggressionF32MH072127 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI YEW, JOANNE Y · 2004 to 2006
$134k
NIDDK NIH HHS DK071801NIDDK NIH HHS R01 DK071801NIDDK NIH HHS R56 DK071801NIGMS NIH HHS GM067645NIGMS NIH HHS GM074675NIGMS NIH HHS R01 GM067645NIGMS NIH HHS R01 GM074675NIMH NIH HHS F32 MH072127
6 · The paper itself

Abstract

A combined approach using mass spectrometry, a novel neuron affinity capture technique, and Drosophila melanogaster genetic manipulation has been developed to characterize the expression and localization of neuropeptides in the adult D. melanogaster brain. In extract from the whole adult brain, 42 neuropeptides from 18 peptide families were sequenced. Neuropeptide profiling also was performed on targeted populations of cells which were enriched with immunoaffinity purification using a genetically expressed marker.

Indexed as

Amino Acid SequenceAnimalsBrainCentral Nervous SystemDrosophila melanogasterMolecular Sequence DataNeuropeptidesSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationNeuropeptides

Identifiers

PMID19199706
PMCPMC2693453

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.