ArticleClinical orthopaedics and related research2009
Case reports: two femoral insufficiency fractures after long-term alendronate therapy.
Article in Clinical orthopaedics and related research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- Delayed healing of lower limb fractures with bisphosphonate therapy.Annals of the Royal College of Surgeons of England · 2015Pooled it
- Long-term administration of quarterly IV ibandronate is effective and well tolerated in postmenopausal osteoporosis: 5-year data from the DIVA study long-term extension.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2012Trial
- Denosumab-associated Periprosthetic Atypical Femur Fracture: A Case Report.Journal of orthopaedic case reports · 2023Article
- Atypical Vancouver B1 Periprosthetic Fractures: The Unsolved Problem.Geriatric orthopaedic surgery & rehabilitation · 2023Article
- Atypical periprosthetic femoral fracture with stem breakage: a case report.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Article
- Preventive bilateral femoral nailing in atypical femoral fracture non responder to anabolic therapy: case report and mini-review.Acta bio-medica : Atenei Parmensis · 2022Article
- Surgical and Pharmacological Management of Periprosthetic Atypical Femoral Fractures: A Narrative Literature Review.Geriatric orthopaedic surgery & rehabilitation · 2022Article
- Atypical periprosthetic femoral fractures after arthroplasty for fracture are at high risk of complications.Scientific reports · 2021Article
- Treatment strategy for atypical ulnar fracture due to severely suppressed bone turnover caused by long-term bisphosphonate therapy: a case report and literature review.BMC musculoskeletal disorders · 2020Review
- Denosumab-Associated Peri-Implant Atypical Femur Fracture: A Case Report.Hawai'i journal of health & social welfare · 2019Article
- Bisphosphonate associated femoral stress fracture distal to an orthopaedic implant: They are predictable!Journal of clinical orthopaedics and trauma · 2019Article
- A Periprosthetic Femoral Fracture with Characteristics of Atypical Femoral Fracture.Case reports in orthopedics · 2019Article
- Two Cases of Periprosthetic Atypical Femoral Fractures in Patients on Long-Term Bisphosphonate Treatment.Case reports in surgery · 2019Article
- Rare non-traumatic periprosthetic femoral fracture with features of an atypical femoral fracture: a case report.Journal of medical case reports · 2015Article
- Association between alendronate and atypical femur fractures: a meta-analysis.Endocrine connections · 2015Article
- Bisphosphonate-associated peri-implant fractures: a new clinical entity? A series of 10 patients with 11 fractures.Acta orthopaedica · 2015Article
- Review: epidemiology and pathophysiology of atypical femur fractures.Current osteoporosis reports · 2014Review
- Bisphosphonate-induced periprosthetic fracture: a cause of painful total hip arthroplasty.Case reports in surgery · 2014Article
- Atypical bilateral femoral shaft fracture in patient treated with bisphosphonates.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2013Article
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Authors and funding
2 authors at 1 institution in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Bisphosphonates are widely used for treatment of postmenopausal osteoporosis. Although short-term safety and efficacy of these drugs have been investigated and documented, an increasing number of recent reports draw attention to the possible correlation between long-term alendronate therapy and the occurrence of insufficiency fractures in the proximal femur owing to what is known as severely suppressed bone turnover. We describe two femoral insufficiency fractures in two women receiving long-term alendronate therapy. The first woman sustained a periprosthetic fracture at the tip of the femoral stem whereas the other woman had a fracture in the subtrochanteric region. We analyze the characteristics and natural course of these two unique fractures, and emphasize the importance of being aware of the possible correlation between long-term alendronate therapy and insufficiency femoral fractures.
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