ArticleJournal of chemical ecology2009
Ecological significance of induction of broad-substrate cytochrome P450s by natural and synthetic inducers in Helicoverpa zea.
Article in Journal of chemical ecology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Complex Roles of Insect Cytochrome P450s in Chemical Adaptation.International journal of biological sciences · 2026Review
- Endemic Yucatan Peninsula Plants with Pesticidal Potential: Herbarium-Based Literature Review.Plants (Basel, Switzerland) · 2024Review
- Physiological and Population Responses ofInsects · 2022Article
- The Effect ofInsects · 2021Article
- Identification of Wild-TypeInsects · 2021Article
- Insects for Food and Feed-Safety Aspects Related to Mycotoxins and Metals.Foods (Basel, Switzerland) · 2019Review
- Identification of Two Cytochrome Monooxygenase P450 Genes, CYP321A7 and CYP321A9, from the Tobacco Cutworm Moth (Spodoptera Litura) and Their Expression in Response to Plant Allelochemicals.International journal of molecular sciences · 2017Article
- Resistance irrelevant CYP417A2v2 was found degrading insecticide inEcology and evolution · 2017Article
- The retardant effect of 2-Tridecanone, mediated by Cytochrome P450, on the Development of Cotton bollworm, Helicoverpa armigera.BMC genomics · 2016Article
- Only a minority of broad-range detoxification genes respond to a variety of phytotoxins in generalist Bemisia tabaci species.Scientific reports · 2015Article
- Expression analysis of two P450 monooxygenase genes of the tobacco cutworm moth (Spodoptera litura) at different developmental stages and in response to plant allelochemicals.Journal of chemical ecology · 2015Article
- Common and unique cis-acting elements mediate xanthotoxin and flavone induction of the generalist P450 CYP321A1.Scientific reports · 2014Article
- Resistance of Australian Helicoverpa armigera to fenvalerate is due to the chimeric P450 enzyme CYP337B3.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Natural history and intragenomic dynamics of the Transib transposon Hztransib in the cotton bollworm Helicoverpa zea.Insect molecular biology · 2011Article
- General guidelines for authors for submission of manuscripts that contain molecular biological content.Journal of chemical ecology · 2010Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The polyphagous corn earworm Helicoverpa zea relies on cytochrome P450 monooxygenases with broad substrate specificities to cope with the wide diversity of phytochemicals it encounters among its numerous host plants. These enzymes also contribute to the ability of this insect to tolerate toxins from sources other than its hosts, including microbial and synthetic toxins. Although upregulation of xenobiotic-metabolizing P450s in some herbivorous insects is closely linked to host plant toxins, transcriptional and/or post-transcriptional regulation of detoxification in this polyphagous species also appears to be relatively unspecialized. Reverse transcription polymerase chain reaction and metabolic analyses indicate that rare and infrequently encountered phytochemicals, as well as synthetic substances, can enhance metabolic activity in an adaptive fashion against both natural and synthetic toxins.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.