ArticleNature neuroscience2009
Spike frequency adaptation mediates looming stimulus selectivity in a collision-detecting neuron.
Article in Nature neuroscience, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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Who cites it
68 citing papers in PubMed.
- Enhanced LGMD Model with Adaptive Probabilistic Regulation for Compound Interference.Biomimetics (Basel, Switzerland) · 2026Article
- Dynamic trajectory cues drive sequenced integration in approach detectors.bioRxiv : the preprint server for biology · 2026Article
- Network structure governs Drosophila brain functionality.Fundamental research · 2026Article
- To jump or not to jump: comparing effects of phenotypic plasticity on the visual responses and escape behavior of locusts and grasshoppers.Journal of neurophysiology · 2026Article
- Harnessing a noncanonical vestibular input in the head-direction network to rectify age-related navigational deficits.Nature aging · 2025Article
- Autonomous retrieval for continuous learning in associative memory networks.Frontiers in computational neuroscience · 2025Article
- Assessing data imbalance correction methods and gaze entropy for collision prediction.PloS one · 2025Article
- Neural networks with optimized single-neuron adaptation uncover biologically plausible regularization.PLoS computational biology · 2024Article
- Modeling the grid cell activity based on cognitive space transformation.Cognitive neurodynamics · 2024Article
- Tonotopic CaJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024Article
- Emotion-gaze interaction affects time-to-collision estimates, but not preferred interpersonal distance towards looming faces.Frontiers in psychology · 2024Article
- Human subcortical pathways automatically detect collision trajectory without attention and awareness.PLoS biology · 2024Article
- Re-framing bio-plausible collision detection: identifying shared meta-properties through strategic prototyping.Frontiers in neurorobotics · 2024Article
- Visual antipredator effects of web flexing in an orb web spider, with special reference to web decorations.Die Naturwissenschaften · 2023Article
- Approaching object acceleration differentially affects the predictions of neuronal collision avoidance models.Biological cybernetics · 2023Article
- Contrast polarity-specific mapping improves efficiency of neuronal computation for collision detection.eLife · 2022Article
- Layer-specific pyramidal neuron properties underlie diverse anterior cingulate cortical motor and limbic networks.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Insect inspired vision-based velocity estimation through spatial pooling of optic flow during linear motion.Bioinspiration & biomimetics · 2021Article
- Interspike interval correlations in neuron models with adaptation and correlated noise.PLoS computational biology · 2021Article
- A model of feedforward, global, and lateral inhibition in the locust visual system predicts responses to looming stimuli.Biological cybernetics · 2021Article
8 more citing papers are in PubMed but not listed here.
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2 authors.
Funding
Abstract
How active membrane conductance dynamics tunes neurons for specific time-varying stimuli remains poorly understood. We studied the biophysical mechanisms by which spike frequency adaptation shapes visual stimulus selectivity in an identified visual interneuron of the locust. The lobula giant movement detector (LGMD) responds preferentially to objects approaching on a collision course with the locust. Using calcium imaging, pharmacology and modeling, we show that spike frequency adaptation in the LGMD is mediated by a Ca(2+)-dependent potassium conductance closely resembling those associated with 'small-conductance' (SK) channels. Intracellular block of this conductance minimally affected the LGMD's response to approaching stimuli, but substantially increased its response to translating ones. Thus, spike frequency adaptation contributes to the neuron's tuning by selectively decreasing its responses to nonpreferred stimuli. Our results identify a new mechanism by which spike frequency adaptation may tune visual neurons to behaviorally relevant stimuli.
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