ArticleNature nanotechnology2009
Multimodal optical sensing and analyte specificity using single-walled carbon nanotubes.
Article in Nature nanotechnology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
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Who cites it
82 citing papers in PubMed.
- Integrating structurally defined DNA-carbon nanotube sensors with machine learning for cancer detection.Science advances · 2026Article
- Optimization of SWCNT-FET Biosensors by Aptamer Engineering and Toehold-Mediated Strand Displacement.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Precision oncology at the nanoscale: nano-optical biosensors for early cancer detection.RSC advances · 2026Review
- Nanomaterial-Enhanced Biosensing: Mechanisms and Emerging Applications.Advanced healthcare materials · 2025Review
- Label-free and real-time monitoring of photoaging with high spatiotemporal resolution using an nIR fluorescent nanosensor array.Science advances · 2025Article
- A salt-driven mechanism for precise chirality sorting of carbon nanotubes.Science advances · 2025Article
- Near-Infrared Fluorescent Single-Walled Carbon Nanotubes for Biosensing.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Hard-Soft Acid-Base Theory Explains Photoexcited Carrier Dynamics in Porphyrin/CNT Nanohybrids: Time-Domain Atomistic Analysis.Journal of the American Chemical Society · 2025Article
- ZnFeMicromachines · 2025Article
- Detection of Estrogen Receptor Status in Breast Cancer Cytology Samples by an Optical Nanosensor.Advanced nanobiomed research · 2025Article
- Development of sterile platform for quantification of extracellular analytes via single walled carbon nanotubes.Analytical biochemistry · 2024Article
- Article
- Development and Evaluation of an Expedited System for Creation of Single Walled Carbon Nanotube Platforms.Carbon letters · 2024Article
- Rapid differentiation of estrogen receptor status in patient biopsy breast cancer aspirates with an optical nanosensor.bioRxiv : the preprint server for biology · 2024Article
- Carbon Nanomaterial Fluorescent Probes and Their Biological Applications.Chemical reviews · 2024Review
- Nanotechnology for the theranostic opportunity of breast cancer lung metastasis: recent advancements and future challenges.Frontiers in bioengineering and biotechnology · 2024Review
- Micro-engineering and nano-engineering approaches to investigate tumour ecosystems.Nature reviews. Cancer · 2023Review
- Numerical Analysis for Light Absorption Spectra of the Base of DNA-Wrapped Single-Walled Carbon Nanotubes.Molecules (Basel, Switzerland) · 2023Article
- On Some Current Challenges in High-Resolution Optical Bioimaging.ACS photonics · 2022Review
- Fluorescent Nanoparticles for Super-Resolution Imaging.Chemical reviews · 2022Review
22 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors.
Funding
Abstract
Nanoscale sensing elements offer promise for single-molecule analyte detection in physically or biologically constrained environments. Single-walled carbon nanotubes have several advantages when used as optical sensors, such as photostable near-infrared emission for prolonged detection through biological media and single-molecule sensitivity. Molecular adsorption can be transduced into an optical signal by perturbing the electronic structure of the nanotubes. Here, we show that a pair of single-walled nanotubes provides at least four modes that can be modulated to uniquely fingerprint agents by the degree to which they alter either the emission band intensity or wavelength. We validate this identification method in vitro by demonstrating the detection of six genotoxic analytes, including chemotherapeutic drugs and reactive oxygen species, which are spectroscopically differentiated into four distinct classes, and also demonstrate single-molecule sensitivity in detecting hydrogen peroxide. Finally, we detect and identify these analytes in real time within live 3T3 cells, demonstrating multiplexed optical detection from a nanoscale biosensor and the first label-free tool to optically discriminate between genotoxins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.