Evidence map›Paper›PMID 19196901›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2009

Sleep-disordered breathing and 24-hour blood pressure pattern among older adults.

Yohannes W Endeshaw, William B White, Michael Kutner, Joseph G Ouslander, Donald L Bliwise

Open access · bronzeAbstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Apneic Sleep, Insufficient Sleep, and Hypertension.Hypertension (Dallas, Tex. : 1979) · 2019
    Review
  8. Sleep, death, and the heart.American journal of physiology. Heart and circulatory physiology · 2015
    Review
  9. Review
  10. Article
  11. Observational
  12. Review
  13. Obstructive sleep apnea and hypertension: an update.Hypertension (Dallas, Tex. : 1979) · 2014
    Review
  14. Article
  15. Article
  16. Neurocognitive correlates of nocturnal oxygen desaturation in a memory clinic population.Journal of clinical and experimental neuropsychology · 2012
    Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yohannes W EndeshawDivision of Geriatrics and Gerontology, Department of Medicine, Emory University School of Medicine, 1841 Clifton Road NE, Atlanta, GA 30329, USA. yendesh@emory.edu
William B White
Michael Kutner
Joseph G Ouslander
Donald L Bliwise
Emory University · USUConn Health · US

Funding

Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
X LINKED NYSTAGMUS SYNDROME WITH FEATURES OF ALBINISMM01RR000039 · NCRR · EMORY UNIVERSITY · PI BRANN, ALFRED W · 1985 to 2007
$21.3M
Mentored Clinical Research Scholar ProgramK12RR017643 · NCRR · EMORY UNIVERSITY · PI BLUMBERG, HENRY M · 2002 to 2006
$5.1M
Nocturnal Polyuria and Sleep-disordered breathingK23AG025963 · NIA · EMORY UNIVERSITY · PI ENDESHAW, YOHANNES W · 2005 to 2009
$636k
NCATS NIH HHS UL1 TR000454NCRR NIH HHS K12 RR 017643NCRR NIH HHS K12 RR017643NCRR NIH HHS M01 RR000039NCRR NIH HHS M01 RR 00039NIA NIH HHS K23 AG 025963NIA NIH HHS K23 AG025963
6 · The paper itself

Abstract

backgroundTo examine the association between sleep-disordered breathing (SDB) and 24-hour blood pressure (BP) pattern among community-dwelling older adults.

methodsA convenience sample of 70 community-dwelling older adults, recruited from senior housing, community centers, and learning centers, were admitted to General Clinical Research Center, Emory University Hospital, Atlanta, Ga. Information regarding demographic and clinical history was obtained using questionnaires. Twenty-four-hour BP monitoring in supine position was performed using Spacelabs model 20207. Breathing during sleep was monitored with the use of a modified sleep recording system (Embletta, PDS), which monitors nasal and oral airflow, chest and abdominal movements, and pulse oximetry. Night time-daytime (night-day) BP ratio (average night-time BP divided by daytime BP) was calculated both for systolic and diastolic BPs.

resultsSixty-nine participants, mean age 74.9 +/- 6.4 years (41 [57%] women), completed the study. The mean apnea-hypopnea index (AHI) was 13 +/- 13 per hour of sleep, and 20 participants (29%) had AHI > or =15 per hour of sleep, indicating moderate to severe SDB. Moderate to severe SDB (AHI > or =15 per hour of sleep) was significantly associated with nocturnal hypertension, whereas there was no statistically significant difference in wake-time BP between those with and without moderate to severe SDB. Stepwise multiple regressions showed that AHI independently predicted increased night-day systolic and night-day diastolic BP ratio, even after controlling for nocturia frequency.

conclusionsThe results indicate increased BP load associated with increased AHI in this group of older adults. This increased BP load may contribute to increased hypertension-related morbidity and disease burden.

Indexed as

AgedAged, 80 and overAge DistributionBlood Pressure Monitoring, AmbulatoryCircadian RhythmComorbidityFemaleFollow-Up StudiesHumansHypertensionIncidenceLinear ModelsMaleMultivariate AnalysisPolysomnographyProbability

Identifiers

PMID19196901
PMCPMC2655030
OpenAlexW2158666036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.