Evidence map›Paper›PMID 19196652›Full record

ReviewPhysiology (Bethesda, Md.)2009

Maternal uterine vascular remodeling during pregnancy.

George Osol, Maurizio Mandala

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 204 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
204citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

204 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum.American journal of physiology. Heart and circulatory physiology · 2024
    Guideline
  2. Trial
  3. Trial
  4. Review
  5. Predictive Factors for Small Head Circumference Among Pregnant Women with Third-Trimester Anemia.International journal of environmental research and public health · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Frontiers in pharmacology · 2026
    Article
  10. Metabolic Signatures of FourMetabolites · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. The uteroplacental circulation at high altitude: adaptation and maladaptation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

144 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

George OsolDepartment of Obstetrics and Gynecology, University of Vermont College of Medicine, Burlington, Vermont, USA. George.Osol@uvm.edu
Maurizio Mandala

Funding

Resistance Artery Adaptation in Hypertensive PregnancyR01HL073895 · NHLBI · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI OSOL, GEORGE J · 2005 to 2009
$1.7M
VERGFR-1 in the Uterine Circulation During PregnancyR01HL079253 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI OSOL, GEORGE J · 2008 to 2011
$1.5M
NHLBI NIH HHS HL-073895NHLBI NIH HHS R01 HL073895NHLBI NIH HHS R01 HL-079253NHLBI NIH HHS R01 HL079253
6 · The paper itself

Abstract

Sufficient uteroplacental blood flow is essential for normal pregnancy outcome and is accomplished by the coordinated growth and remodeling of the entire uterine circulation, as well as the creation of a new fetal vascular organ: the placenta. The process of remodeling involves a number of cellular processes, including hyperplasia and hypertrophy, rearrangement of existing elements, and changes in extracellular matrix. In this review, we provide information on uterine blood flow increases during pregnancy, the influence of placentation type on the distribution of uterine vascular resistance, consideration of the patterns, nature, and extent of maternal uterine vascular remodeling during pregnancy, and what is known about the underlying cellular mechanisms.

Indexed as

AnimalsArteriesExtracellular MatrixFemaleHumansMaternal-Fetal ExchangePlacentaPregnancyUterusVascular Resistance

Identifiers

PMID19196652
PMCPMC2760472

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.