ReviewCurrent opinion in cell biology2009
Centriole evolution.
Review in Current opinion in cell biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Life sets off a cascade of machines.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The kinase ZYG-1 phosphorylates the cartwheel protein SAS-5 to drive centriole assembly in C. elegans.EMBO reports · 2024Article
- Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.Structure (London, England : 1993) · 2022Article
- The Centriole's Role in Miscarriages.Frontiers in cell and developmental biology · 2022Article
- Expansion microscopy of Plasmodium gametocytes reveals the molecular architecture of a bipartite microtubule organisation centre coordinating mitosis with axoneme assembly.PLoS pathogens · 2022Article
- Islet cilia and glucose homeostasis.Frontiers in cell and developmental biology · 2022Review
- Structure of Motile Cilia.Sub-cellular biochemistry · 2022Article
- The Cilioprotist Cytoskeleton , a Model for Understanding How Cell Architecture and Pattern Are Specified: Recent Discoveries from Ciliates and Comparable Model Systems.Methods in molecular biology (Clifton, N.J.) · 2022Review
- Mechanical Mechanisms of Chromosome Segregation.Cells · 2021Review
- Identification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerization.The Journal of biological chemistry · 2020Article
- Choreography of the centrosome.Heliyon · 2020Review
- A dynamically interacting flexible loop assists oligomerisation of the Caenorhabditis elegans centriolar protein SAS-6.Scientific reports · 2019Article
- Article
- Evolution of Cilia.Cold Spring Harbor perspectives in biology · 2017Review
- PLATINUM SENSITIVE 2 LIKE impacts growth, root morphology, seed set, and stress responses.PloS one · 2017Article
- Review
- Viral Agents Causing Brown Cap Mushroom Disease of Agaricus bisporus.Applied and environmental microbiology · 2015Article
- Evolutionary problems in centrosome and centriole biology.Journal of evolutionary biology · 2015Review
- Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells.The Journal of cell biology · 2014Article
- A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar components.Eukaryotic cell · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Centrioles are cylindrical structures found at the core of the mitotic spindle pole, which also act as basal bodies to nucleate the formation of cilia. Centrioles have a complex, ninefold symmetric structure, and reproduce by an intriguing duplication process. The complexity and apparent self-reproduction of centrioles raises the question of how such a structure could have evolved, making them a favorite topic for theological speculation by 'intelligent design' creationists. In fact, centrioles are capable of robust self-assembly and can tolerate dramatic perturbations while still maintaining basic functionality. Far from being irreducibly complex, centrioles appear to be based on a rather minimal underlying core structure requiring only a handful of genes to construct.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.