Evidence map›Paper›PMID 19195055›Full record

ReviewWorld journal of gastroenterology2009

Hepcidin modulation in human diseases: from research to clinic.

Alberto Piperno, Raffaella Mariani, Paola Trombini, Domenico Girelli

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Trial
  2. Article
  3. Iron Status and Physical Performance in Athletes.Life (Basel, Switzerland) · 2023
    Review
  4. Hepcidin as a Potential Biomarker for the Diagnosis of Anemia.Turkish journal of pharmaceutical sciences · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Inherited iron overload disorders.Translational gastroenterology and hepatology · 2020
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Myelodysplastic Syndromes and Iron Chelation Therapy.Mediterranean journal of hematology and infectious diseases · 2017
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alberto PipernoDepartment of Clinical Medicine and Prevention, University of Milano-Bicocca, S. Gerardo Hospital, Via Pergolesi 33, 20052, Monza, Italy. alberto.piperno@unimib.it
Raffaella Mariani
Paola Trombini
Domenico Girelli

Funding

Telethon GGP06213
6 · The paper itself

Abstract

By modulating hepcidin production, an organism controls intestinal iron absorption, iron uptake and mobilization from stores to meet body iron need. In recent years there has been important advancement in our knowledge of hepcidin regulation that also has implications for understanding the physiopathology of some human disorders. Since the discovery of hepcidin and the demonstration of its pivotal role in iron homeostasis, there has been a substantial interest in developing a reliable assay of the hormone in biological fluids. Measurement of hepcidin in biological fluids can improve our understanding of iron diseases and be a useful tool for diagnosis and clinical management of these disorders. We reviewed the literature and our own research on hepcidin to give an updated status of the situation in this rapidly evolving field.

Indexed as

AnimalsAnti-Infective AgentsAntimicrobial Cationic PeptidesErythropoiesisGene Expression RegulationHemochromatosisHemochromatosis ProteinHepcidinsHistocompatibility Antigens Class IHomeostasisHumansIronMembrane ProteinsModels, AnimalReceptors, TransferrinTranscription, GeneticAnti-Infective AgentsAntimicrobial Cationic PeptidesHAMP protein, humanHemochromatosis ProteinHepcidinsHFE protein, humanHistocompatibility Antigens Class IIronMembrane ProteinsReceptors, TransferrinTFR2 protein, human

Identifiers

PMID19195055
PMCPMC2653344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.