Evidence map›Paper›PMID 19194774›Full record

ArticleLa Radiologia medica2009

Contrast-enhanced breast MR imaging of claustrophobic or oversized patients using an open low-field magnet.

M Calabrese, D Brizzi, L Carbonaro, M Chiaramondia, M A Kirchin, F Sardanelli

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Article in La Radiologia medica, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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3 · Its place in the literature

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5 citing papers in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

M CalabreseUnit of Breast Imaging, University of Genoa and San Martino Hospital, Largo Rosanna Benzi 10, 16132, Genoa, Italy.
D Brizzi
L Carbonaro
M Chiaramondia
M A Kirchin
F Sardanelli

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA number of women who should undergo magnetic resonance (MR) imaging of the breast cannot use this diagnostic tool due to claustrophobia or excessive body size for the restricted confines of standard closed MR systems. Our aim was to evaluate the performance of open low-field magnet breast MR imaging in such patients using a high-relaxivity contrast agent. MATERIALS AND

methodsOf 397 consecutive patients undergoing breast MR imaging, 379 (95.5%) were studied at 1.5 T. Due to claustrophobia (n=15) or large body size (n=3), 18 patients (4.5%) were studied on a 0.2-T open magnet using a body coil. A 3D dynamic T1-weighted gradient-echo 94-s sequence was acquired with intravenous injection of gadobenate dimeglumine (0.1 mmol/kg). The standard of reference was pathological examination for 16 lesions classified with a maximal Breast Imaging Reporting and Data System (BI-RADS) score from 3 to 5, fine-needle aspiration cytology and >or=2-year follow-up for two lesions classified as BI-RADS 3, and >or=2-years follow-up for five lesions classified as BI-RADS 2.

resultsDiagnostic MR image quality was achieved for 20/23 lesions in 15/18 patients. Three lesions (two invasive cancers and a cyst) were not assessed due to patient movement and considered as two false negatives and one false positive. Thus, an 86% sensitivity [13/15; 95% confidence interval (CI): 70%-100%], an 87% specificity (7/8; 95% CI: 65%-100%) and an 87% accuracy (20/23; 95% CI: 73%-100%) were obtained. The intraclass correlation coefficient between MR and pathologic lesion size was 0.845.

conclusionIn claustrophobic or oversized patients, open low-field breast MR with gadobenate dimeglumine yields good diagnostic performance.

Indexed as

Contrast MediaOrganometallic CompoundsOverweightAdultAgedAged, 80 and overBreastBreast NeoplasmsEquipment DesignFemaleHumansImage EnhancementMagnetic Resonance ImagingMeglumineMiddle AgedPhobic DisordersContrast Mediagadobenic acidMeglumineOrganometallic Compounds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.