ArticleMedical microbiology and immunology2009
Seroprevalence of influenza A and B in German infants and adolescents.
Article in Medical microbiology and immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 54 citations in OpenAlex.
- Positive network assortativity of influenza vaccination at a high school: implications for outbreak risk and herd immunity.PloS one · 2014Trial
- The ageing immune system and its battle with viruses.The Journal of general virology · 2026Review
- Estimating community-wide indirect effects of influenza vaccination: triangulation using mathematical models and bias analysis.American journal of epidemiology · 2025Article
- Early influenza virus exposure shapes the B cell response to influenza vaccination in individuals 50 years later.Immunity · 2025Article
- Immune imprinting in early life shapes cross-reactivity to influenza B virus haemagglutinin.Nature microbiology · 2024Article
- Seroprevalence of Protective Antibodies Against Influenza and the Reduction of the Influenza Incidence Rate: An Annual Repeated Cross-Sectional Study From 2014 to 2019.Influenza and other respiratory viruses · 2024Article
- Incidence and seroprevalence of seasonal influenza a viruses in Egypt: Results of a community-based cohort study.Influenza and other respiratory viruses · 2022Article
- Epidemiological characteristics of imported respiratory infectious diseases in China, 2014‒2018.Infectious diseases of poverty · 2022Article
- Similar severity of influenza primary and re-infections in pre-school children requiring outpatient treatment due to febrile acute respiratory illness: prospective, multicentre surveillance study (2013-2015).BMC infectious diseases · 2022Article
- Incidence and neutralizing antibody seroprevalence of influenza B virus in Egypt: Results of a community-based cohort study.PloS one · 2022Article
- Factors Influencing Frequency of Pediatric Clinically Distinguishable Influenza: A 2 Season Case-Control Study.Clinical medicine insights. Pediatrics · 2022Article
- Article
- Influenza vaccine effectiveness estimates against influenza A(H3N2) and A(H1N1) pdm09 among children during school-based outbreaks in the 2016-2017 season in Beijing, China.Human vaccines & immunotherapeutics · 2020Article
- Influenza in the school-aged population in Mexico: burden of disease and cost-effectiveness of vaccination in children.BMC infectious diseases · 2020Article
- Epidemiology and molecular characterization of influenza viruses in Burkina Faso, sub-Saharan Africa.Influenza and other respiratory viruses · 2018Article
- Potent protection against H5N1 and H7N9 influenza via childhood hemagglutinin imprinting.Science (New York, N.Y.) · 2016Article
- Explaining the geographical origins of seasonal influenza A (H3N2).Proceedings. Biological sciences · 2016Article
- Technical guidelines for the application of seasonal influenza vaccine in China (2014-2015).Human vaccines & immunotherapeutics · 2015Article
- How much of virus-specific CD8 T cell reactivity is detected with a peptide pool when compared to individual peptides?Viruses · 2012Article
- Serological response to influenza A H1N1 vaccine (Pandemrix®) and seasonal influenza vaccine 2009/2010 in renal transplant recipients and in hemodialysis patients.Medical microbiology and immunology · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to provide seroepidemiological information on influenza A and B antibodies in children and adolescents. Viral immunoglobulin G antibodies were determined retrospectively using enzyme-linked immunosorbent assays in a group of 1,111 children and adolescents. Sera (809) from healthy adult blood donors served as controls. In children, the prevalence of antibodies against influenza A was 82.0% and against influenza B 9.6%, whereas in adults the prevalence of antibodies against influenza A was calculated as 99.4% and against influenza B 56.7%. After decline of maternal antibodies during the first year of life, there was an increase of prevalence of influenza A antibodies up to 100% by the age of 12 years. In contrast, only 1-2% of children up to 9 years had influenza B antibodies increasing to 25% by the age of 18 years and to 70% among adults aged 30 years. Children aged 0-6 years had significantly lower concentrations and >12-15-year-old adolescents had significantly higher concentrations of antibodies against influenza A than adults. For all age groups of children and adolescents, significantly lower antibody concentrations against influenza B were measured in comparison to the blood donor control group. In conclusion, the annual influenza vaccination in children and adolescents may improve considerably the protection against influenza virus infection occurring during epidemics.
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