Evidence map›Paper›PMID 19194203›Full record

ArticleJournal of pediatric hematology/oncology2009

Unusual sites of extraskeletal metastases of Ewing sarcoma after allogeneic hematopoietic stem cell transplantation.

Christian M Capitini, Joanne Derdak, Marybeth S Hughes, Cynthia P Love, Kristin Baird, Crystal L Mackall, Terry J Fry

Registry-linked trialOpen access · greenAbstract readCase Reports
In one paragraph

Article in Journal of pediatric hematology/oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02653196 (A Multi-Institutional Pilot Study of Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Malignant Neuro-Epithelial and Other Solid Tumors), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02653196 early_phase1terminatednot on this mapstarted 2015, after this paper: background citation

A Multi-Institutional Pilot Study of Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Malignant Neuro-Epithelial and Other Solid Tumors

TypeinterventionalSponsorMontefiore Medical CenterRan2015 to 2017Enrolled1ConditionsNeuroepithelial Tumor, Solid Tumor, Allogeneic Hematopoietic Stem Cell TransplantationArmsAllogeneic hematopoietic stem cell transplant following thiotepa-based marrow ablative chemotherapy, Keratinocyte Growth Factor, Alemtuzumab, Thiotepa, Etoposide
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Christian M CapitiniPediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. capitinic@mail.nih.gov
Joanne Derdak
Marybeth S Hughes
Cynthia P Love
Kristin Baird
Crystal L Mackall
Terry J Fry
Pediatric Oncology Group · CANational Institutes of Health · US

Funding

Clinical Program in Pediatric SarcomasZIABC011074 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MACKALL, CRYSTAL · 2009 to 2012
$5.2M
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Allogeneic stem cell transplantation (SCT) for solid tumors remains under investigation. We report a case of extended disease stability after a nonmyeloablative peripheral blood SCT for metastatic, refractory Ewing sarcoma. Of note, the patient developed metastatic disease to 2 unusual sites-the brain and small intestine. The allogeneic SCT environment may alter typical metastatic patterns, and may represent an ideal platform to manipulate and enhance the antitumor immune response. Further clinical trials are needed to evaluate the role for allogeneic SCT for this disease.

Indexed as

AdultBrain NeoplasmsHematopoietic Stem Cell TransplantationHumansIntestinal NeoplasmsMaleNeoplasm MetastasisSarcoma, EwingTransplantation, HomologousTreatment Failure

Identifiers

PMID19194203
PMCPMC2644462
OpenAlexW1994808823

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.