Evidence map›Paper›PMID 19192246›Full record

ReviewTraffic (Copenhagen, Denmark)2009

Basal body assembly in ciliates: the power of numbers.

Chad G Pearson, Mark Winey

Abstract readReview
In one paragraph

Review in Traffic (Copenhagen, Denmark), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Journal of cell science · 2020
    Article
  5. Article
  6. Review
  7. Article
  8. Polarity in Ciliate Models: From Cilia to Cell Architecture.Frontiers in cell and developmental biology · 2019
    Review
  9. Motile Cilia: Innovation and Insight From Ciliate Model Organisms.Frontiers in cell and developmental biology · 2019
    Review
  10. Article
  11. Cell chirality: its origin and roles in left-right asymmetric development.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016
    Review
  12. Article
  13. Article
  14. Review
  15. Evolution of the nucleus.Current opinion in cell biology · 2014
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chad G PearsonMolecular, Cellular, and Developmental Biology, University of Colorado-Boulder, 347 UCB, Porter Biosciences, Boulder, CO 80309-0347, USA. chad.pearson@colorado.edu
Mark Winey

Funding

Tetrahymena Basal Body DuplicationR01GM074746 · NIGMS · UNIVERSITY OF COLORADO · PI WINEY, MARK · 2006 to 2015
$3.0M
NIGMS NIH HHS GM074746NIGMS NIH HHS R01 GM074746
6 · The paper itself

Abstract

Centrioles perform the dual functions of organizing both centrosomes and cilia. The biogenesis of nascent centrioles is an essential cellular event that is tightly coupled to the cell cycle so that each cell contains only two or four centrioles at any given point in the cell cycle. The assembly of centrioles and their analogs, basal bodies, is well characterized at the ultrastructural level whereby structural modules are built into a functional organelle. Genetic studies in model organisms combined with proteomic, bioinformatic and identifying ciliary disease gene orthologs have revealed a wealth of molecules requiring further analysis to determine their roles in centriole duplication, assembly and function. Nonetheless, at this stage, our understanding of how molecular components interact to build new centrioles and basal bodies is limited. The ciliates, Tetrahymena and Paramecium, historically have been the subject of cytological and genetic study of basal bodies. Recent advances in the ciliate genetic and molecular toolkit have placed these model organisms in a favorable position to study the molecular mechanisms of centriole and basal body assembly.

Indexed as

AnimalsCell CycleCentriolesCentrosomeCiliaCiliophoraOrganellesParameciumTetrahymena

Identifiers

PMID19192246
PMCPMC2743681

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.