Evidence map›Paper›PMID 19190954›Full record

ReviewBasic research in cardiology2009

Vascular control in humans: focus on the coronary microcirculation.

Yanping Liu, David D Gutterman

Abstract readReview
In one paragraph

Review in Basic research in cardiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
  2. Review
  3. Unraveling the Gordian knot of coronary pressure-flow autoregulation.Journal of molecular and cellular cardiology · 2024
    Review
  4. Review
  5. Ischemic Heart Disease and Heart Failure: Role of Coronary Ion Channels.International journal of molecular sciences · 2020
    Review
  6. Article
  7. Review
  8. Microvascular Coronary Dysfunction-an Overview.Current atherosclerosis reports · 2018
    Review
  9. Shaker-related voltage-gated KMicrocirculation (New York, N.Y. : 1994) · 2018
    Article
  10. Article
  11. Article
  12. Article
  13. Regulation of Coronary Blood Flow.Comprehensive Physiology · 2017
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Reduced vascular smooth muscle BK channel current underlies heart failure-induced vasoconstriction in mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yanping LiuNational Center for Research Resources, NIH, Bethesda, MD, USA.
David D Gutterman

Funding

Flow-Mediated Dilation of Human Coronary ArteriolesR01HL080704 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI GUTTERMAN, DAVID D. · 2006 to 2010
$1.8M
High glucose and arteriolar Kv channelsR01HL067968 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI GUTTERMAN, DAVID D. · 2003 to 2006
$1.4M
NHLBI NIH HHS R01 HL067968NHLBI NIH HHS R01 HL080704
6 · The paper itself

Abstract

Myocardial perfusion is regulated by a variety of factors that influence arteriolar vasomotor tone. An understanding of the physiological and pathophysiological factors that modulate coronary blood flow provides the basis for the judicious use of medications for the treatment of patients with coronary artery disease. Vasomotor properties of the coronary circulation vary among species. This review highlights the results of recent studies that examine the mechanisms by which the human coronary microcirculation is regulated in normal and disease states, focusing on diabetes. Multiple pathways responsible for myogenic constriction and flow-mediated dilation in human coronary arterioles are addressed. The important role of endothelium-derived hyperpolarizing factors, their interactions in mediating dilation, as well as speculation regarding the clinical significance are emphasized. Unique properties of coronary arterioles in human vs. other species are discussed.

Indexed as

Cardiovascular Physiological PhenomenaCoronary CirculationHumansMicrocirculation

Identifiers

PMID19190954
PMCPMC3045058

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.