ArticleJournal of experimental botany2009
A naturally occurring splicing site mutation in the Brassica rapa FLC1 gene is associated with variation in flowering time.
Article in Journal of experimental botany, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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61 citing papers in PubMed.
- The Bra1K array: an efficient and versatile 1K liquid-phase SNP chip for genetics and breeding in Chinese cabbage.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Temporal Transcriptome Analysis Reveals Core Pathways and Orphan GenePlants (Basel, Switzerland) · 2025Article
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- Genome-wide characterization of the MADS-box gene family in Paeonia ostii and expression analysis of genes related to floral organ development.BMC genomics · 2025Article
- Construction and evaluation ofFrontiers in plant science · 2025Article
- All roads lead to Rome: QTL analysis for vernalization requirement and dissection of allelic variation uncovered unexpected diversity ofFrontiers in plant science · 2025Article
- Orphan geneHorticulture research · 2024Article
- Contribution of homoeologous exchange to domestication of polyploid Brassica.Genome biology · 2024Article
- Fine mapping and analysis of candidate genes for qBT2 and qBT7.2 locus controlling bolting time in radish (Raphanus sativus L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Characterization ofMolecular breeding : new strategies in plant improvement · 2023Article
- Non-vernalization requirement for flowering in Brassica rapa conferred by a dominant allele of FLOWERING LOCUS T.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- The genome of Orychophragmus violaceus provides genomic insights into the evolution of Brassicaceae polyploidization and its distinct traits.Plant communications · 2023Article
- Epistatic interactions among multiple copies ofAoB PLANTS · 2023Article
- Article
- Fine mapping and analysis of candidate genes for qFT7.1, a major quantitative trait locus controlling flowering time in Brassica rapa L.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- A premature stop codon in BrFLC2 transcript results in early flowering in oilseed-type Brassica rapa plants.Plant molecular biology · 2022Article
- Non-vernalization requirement in Chinese kale caused by loss of BoFLC and low expressions of its paralogs.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Their C-termini divideFrontiers in plant science · 2022Article
- Investigation ofHorticulture research · 2022Article
- A single amino acid residue substitution in BraA04g017190.3C, a histone methyltransferase, results in premature bolting in Chinese cabbage (Brassica rapa L. ssp. Pekinensis).BMC plant biology · 2021Article
1 more citing papers are in PubMed but not listed here.
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7 authors.
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Abstract
FLOWERING LOCUS C (FLC), encoding a MADS-domain transcription factor in Arabidopsis, is a repressor of flowering involved in the vernalization pathway. This provides a good reference for Brassica species. Genomes of Brassica species contain several FLC homologues and several of these colocalize with flowering-time QTL. Here the analysis of sequence variation of BrFLC1 in Brassica rapa and its association with the flowering-time phenotype is reported. The analysis revealed that a G-->A polymorphism at the 5' splice site in intron 6 of BrFLC1 is associated with flowering phenotype. Three BrFLC1 alleles with alternative splicing patterns, including two with different parts of intron 6 retained and one with the entire exon 6 excluded from the transcript, were identified in addition to alleles with normal splicing. It was inferred that aberrant splicing of the pre-mRNA leads to loss-of-function of BrFLC1. A CAPS marker was developed for this locus to distinguish Pi6+1(G) and Pi6+1(A). The polymorphism detected with this marker was significantly associated with flowering time in a collection of 121 B. rapa accessions and in a segregating Chinese cabbage doubled-haploid population. These findings suggest that a naturally occurring splicing mutation in the BrFLC1 gene contributes greatly to flowering-time variation in B. rapa.
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