ArticleNucleic acids research2009
A synthetic mammalian electro-genetic transcription circuit.
Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed, 61 citations in OpenAlex.
- Implantable Light-Powered Human Designer Cells for Electrical Energy Generation.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Electrochemistry as a Tool for Redox-Based Bio-Information Processing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- An electrogenetic interface to program mammalian gene expression by direct current.Nature metabolism · 2023Article
- Living electronics: A catalogue of engineered living electronic components.Microbial biotechnology · 2023Review
- Next-generation engineered microsystems for cell biology: a systems-level roadmap.Trends in cell biology · 2022Review
- Electrogenetic Signal Transmission and Propagation in Coculture to Guide Production of a Small Molecule, Tyrosine.ACS synthetic biology · 2022Article
- Electronic signals are electrogenetically relayed to control cell growth and co-culture composition.Metabolic engineering communications · 2021Article
- Synthetic biology as driver for the biologization of materials sciences.Materials today. Bio · 2021Review
- Robust direct digital-to-biological data storage in living cells.Nature chemical biology · 2021Article
- Review
- Review
- SCHEEPDOG: Programming Electric Cues to Dynamically Herd Large-Scale Cell Migration.Cell systems · 2020Article
- Bottom-up approaches in synthetic biology and biomaterials for tissue engineering applications.Journal of industrial microbiology & biotechnology · 2018Article
- Electronic control of gene expression and cell behaviour in Escherichia coli through redox signalling.Nature communications · 2017Article
- Mammalian synthetic biology: emerging medical applications.Journal of the Royal Society, Interface · 2015Review
- Article
- The bacterial nanorecorder: engineering E. coli to function as a chemical recording device.PloS one · 2011Article
- Synthetic biology: applications come of age.Nature reviews. Genetics · 2010Review
- Modular electron transfer circuits for synthetic biology: insulation of an engineered biohydrogen pathway.Bioengineered bugsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electric signal processing has evolved to manage rapid information transfer in neuronal networks and muscular contraction in multicellular organisms and controls the most sophisticated man-built devices. Using a synthetic biology approach to assemble electronic parts with genetic control units engineered into mammalian cells, we designed an electric power-adjustable transcription control circuit able to integrate the intensity of a direct current over time, to translate the amplitude or frequency of an alternating current into an adjustable genetic readout or to modulate the beating frequency of primary heart cells. Successful miniaturization of the electro-genetic devices may pave the way for the design of novel hybrid electro-genetic implants assembled from electronic and genetic parts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.