ReviewVirchows Archiv : an international journal of pathology2010
Genomic characteristics of soft tissue sarcomas.
Review in Virchows Archiv : an international journal of pathology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 36 citations in OpenAlex.
- Well-Differentiated Liposarcoma (Atypical Lipomatous Tumor) Presenting as an Esophageal Polyp.Journal of gastrointestinal cancer · 2019Article
- Disseminated Hemangiosarcoma in a Juvenile Rhesus Macaque (Macaca mulatta).Comparative medicine · 2016Article
- Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway.Oncotarget · 2015Article
- Well-differentiated angiosarcoma of spleen: a teaching case mimicking hemagioma and cytogenetic analysis with array comparative genomic hybridization.World journal of surgical oncology · 2015Article
- Article
- The surgeon and molecular knowledge.The Indian journal of surgery · 2013Article
- Analysis of PTEN methylation patterns in soft tissue sarcomas by MassARRAY spectrometry.PloS one · 2013Article
- Article
- Advances in sarcoma genomics and new therapeutic targets.Nature reviews. Cancer · 2011Review
- Dog models of naturally occurring cancer.Trends in molecular medicine · 2011Review
- [Histological classification of soft tissue tumors and staging according to the TNM system].Der Pathologe · 2011Review
- Cytogenetics and molecular genetics of myxoid soft-tissue sarcomas.Genetics research international · 2011Article
- Soft tissue sarcomas: introduction to the Virchows Archiv review issue.Virchows Archiv : an international journal of pathology · 2010Article
- Molecular basis of differentiation therapy for soft tissue sarcomas.Trends in cancer researchArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies on the molecular mechanisms behind soft tissue sarcoma development have disclosed that these malignancies are as genetically heterogeneous as they are clinically and morphologically diverse. Much of the genetic information on soft tissue sarcomas is still limited to the genomic level, as detected by chromosome banding analysis or comparative genomic hybridization. Based on the results of such studies, soft tissue sarcomas may be broadly dichotomized into one group, accounting for approximately 20% of the cases, characterized by specific balanced translocations, and one group typically showing massive chromosomal rearrangements leading to recurrent, but non-specific, structural and numerical rearrangements. As summarized in this review, the genomic characterization of soft tissue sarcomas has not only provided cell biologists with decisive information on the parts of the genome that may harbor genes that are essential for tumor development but also given the clinicians involved in the management of these patients a valuable diagnostic tool.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.