Evidence map›Paper›PMID 19188056›Full record

ReviewCurrent opinion in cell biology2009

Regulation of peroxisome dynamics.

Jennifer J Smith, John D Aitchison

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Localization of a Trypanosome Peroxin to the Endoplasmic Reticulum.The Journal of eukaryotic microbiology · 2017
    Article
  7. Review
  8. Peroxisomal biogenesis in ischemic brain.Antioxidants & redox signaling · 2015
    Article
  9. Peroxisomes take shape.Nature reviews. Molecular cell biology · 2013
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jennifer J SmithInstitute for Systems Biology, 1441 N 34th Street, Seattle, WA 98103, USA. jsmith@systemsbiology.org
John D Aitchison

Funding

Quantitative Systems BiologyP50GM076547 · NIGMS · INSTITUTE FOR SYSTEMS BIOLOGY · PI BALIGA, NITIN S · 2006 to 2016
$30.6M
NEW TOOLS FOR EXPLORING THE DYNAMIC INTERACTOME(RMI)U54RR022220 · NCRR · ROCKEFELLER UNIVERSITY · PI ROUT, MICHAEL P · 2005 to 2011
$19.3M
Oleate-responsive gene regulatory networks governing peroxisome proliferationR01GM075152 · NIGMS · SEATTLE BIOMEDICAL RESEARCH INSTITUTE · PI AITCHISON, JOHN D. · 2008 to 2011
$1.9M
NCRR NIH HHS U54 RR022220NIGMS NIH HHS P50 GM076547NIGMS NIH HHS R01 GM075152
6 · The paper itself

Abstract

Peroxisomes are single-membraned organelles ubiquitous to eukaryotic cells that house metabolic reactions that generate and destroy harmful oxidative intermediates. They are dynamic structures whose morphology, abundance, composition, and function depend on the cell type and environment. Perhaps due to the potentially damaging and protective metabolic roles of peroxisomes and their dynamic presence in the cell, peroxisome biogenesis is emerging as a process that involves complex underlying mechanisms of regulated formation and maintenance. There are roughly 30 known peroxins, proteins involved in peroxisome biogenesis, many of which have been conserved from yeast to mammals. This review focuses on the biogenesis of peroxisomes with an emphasis on the regulation of peroxisome formation and the import of peroxisomal matrix proteins in the model organism Saccharomyces cerevisiae.

Indexed as

Membrane ProteinsModels, MolecularPeroxisomesSaccharomyces cerevisiaeMembrane Proteins

Identifiers

PMID19188056
PMCPMC2681484

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.