Evidence map›Paper›PMID 19187778›Full record

ReviewExperimental parasitology2010

Cryptosporidium: genomic and biochemical features.

Stanley Dean Rider, Guan Zhu

Abstract readReview
In one paragraph

Review in Experimental parasitology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. In Vitro Inhibition ofPathogens (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Pyrimidine salvage inFrontiers in cellular and infection microbiology · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Microbial genomics · 2021
    Article
  18. Article
  19. Article
  20. Current clinical microbiology reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stanley Dean RiderDepartment of Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, 4467 TAMU, College Station, TX 77843, USA. drider@cvm.tamu.edu
Guan Zhu

Funding

FATTY ACID BIOSYTHESIS IN CRYPTOSPORIDIUM PARVUMR01AI044594 · NIAID · WADSWORTH CENTER · PI ZHU, GUAN · 2000 to 2010
$2.8M
Cryptosporidium parvum DNA replication proteinsR21AI055278 · NIAID · TEXAS A&M UNIVERSITY SYSTEM · PI ZHU, GUAN · 2003 to 2004
$437k
Host cell proteins that interact with CryptosporidiumR21AI080022 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI ZHU, GUAN · 2008 to 2009
$403k
Cryptosporidium parvum Histone DeacetylasesR21AI068461 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI RIDER, STANLEY DEAN · 2006 to 2007
$395k
NIAID NIH HHS AI055278NIAID NIH HHS AI068461NIAID NIH HHS AI44594NIAID NIH HHS R01 AI044594NIAID NIH HHS R21 AI055278NIAID NIH HHS R21 AI068461NIAID NIH HHS R21 AI080022
6 · The paper itself

Abstract

Recent progress in understanding the unique biochemistry of the two closely related human enteric pathogens Cryptosporidium parvum and Cryptosporidium hominis has been stimulated by the elucidation of the complete genome sequences for both pathogens. Much of the work that has occurred since that time has been focused on understanding the metabolic pathways encoded by the genome in hopes of providing increased understanding of the parasite biology, and in the identification of novel targets for pharmacological interventions. However, despite identifying the genes encoding enzymes that participate in many of the major metabolic pathways, only a hand full of proteins have actually been the subjects of detailed scrutiny. Thus, much of the biochemistry of these parasites remains a true mystery.

Indexed as

GenomeAmino AcidsCarbohydrate MetabolismCryptosporidiosisCryptosporidiumCryptosporidium parvumDNA, ProtozoanGene Expression RegulationHumansLipid MetabolismMembrane Transport ProteinsNucleotidesPolyaminesProteomicsProtozoan ProteinsAmino AcidsDNA, ProtozoanMembrane Transport ProteinsNucleotidesPolyaminesProtozoan Proteins

Identifiers

PMID19187778
PMCPMC2819285

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.