ReviewNeuron2009
Glia, adenosine, and sleep.
Review in Neuron, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Sleep debt elicits negative emotional reaction through diminished amygdala-anterior cingulate functional connectivity.PloS one · 2013Trial
- Extracellular adenosine induces hypersecretion of IL-17A by T-helper 17 cells through the adenosine A2a receptor.Brain, behavior, & immunity - health · 2022Article
- Adenosine Downregulates the Activities of Glutamatergic Neurons in the Paraventricular Hypothalamic Nucleus Required for Sleep.Frontiers in neuroscience · 2022Article
- Metabolism of sleep and aging: Bridging the gap using metabolomics.Nutrition and healthy aging · 2019Review
- Astrocyte Changes in the Prefrontal Cortex From Aged Non-suicidal Depressed Patients.Frontiers in cellular neuroscience · 2019Article
- Article
- Recovery sleep after extended wakefulness restores elevated AProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Article
- Augmented generation of protein fragments during wakefulness as the molecular cause of sleep: a hypothesis.Protein science : a publication of the Protein Society · 2012Article
- Circadian regulation of ATP release in astrocytes.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- The role of ATP in sleep regulation.Frontiers in neurology · 2011Article
- Functional Anatomy of Non-REM Sleep.Frontiers in neurology · 2011Article
- Purines and the Anti-Epileptic Actions of Ketogenic Diets.The open neuroscience journal · 2010Article
Corrections and comments
- Comment on
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep is regulated by a homeostatic process that has long been thought to involve adenosine (AD) originating from neurons. In this issue of Neuron, Halassa et al. present evidence that sleep homeostasis depends upon gliotransmission and associated accumulation of AD that dampens neuronal excitability.
Indexed as
Identifiers
19186158What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.