Evidence map›Paper›PMID 19185946›Full record

ArticleComputer methods and programs in biomedicine2009

Arrowsmith two-node search interface: a tutorial on finding meaningful links between two disparate sets of articles in MEDLINE.

Neil R Smalheiser, Vetle I Torvik, Wei Zhou

Abstract read
In one paragraph

Article in Computer methods and programs in biomedicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Tracking and Mining the COVID-19 Research Literature.Frontiers in research metrics and analytics · 2020
    Article
  9. Article
  10. Ketamine: A Neglected Therapy for Alzheimer Disease.Frontiers in aging neuroscience · 2019
    Article
  11. MELODI: Mining Enriched Literature Objects to Derive Intermediates.International journal of epidemiology · 2018
    Article
  12. MOLIERE: Automatic Biomedical Hypothesis Generation System.KDD : proceedings. International Conference on Knowledge Discovery & Data Mining · 2017
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Mammalian Argonaute-DNA binding?Biology direct · 2014
    Article
  18. Article
  19. Article
  20. Studying PubMed usages in the field for complex problem solving: Implications for tool design.Journal of the American Society for Information Science and Technology : JASIST · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Neil R SmalheiserDepartment of Psychiatry and Psychiatric Institute, MC912, University of Illinois at Chicago, 1601W. Taylor Street, Chicago, IL 60612, USA. neils@uic.edu
Vetle I Torvik
Wei Zhou

Funding

Arrowsmith Data Mining Techniques in Neuro-InformaticsR01LM007292 · NLM · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SMALHEISER, NEIL R · 2001 to 2005
$3.2M
Author Name Disambiguation in MedlineR21LM008364 · NLM · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SMALHEISER, NEIL R · 2005 to 2006
$372k
NLM NIH HHS LM007292NLM NIH HHS LM008364NLM NIH HHS R01 LM007292NLM NIH HHS R21 LM008364
6 · The paper itself

Abstract

The Arrowsmith two-node search is a strategy that is designed to assist biomedical investigators in formulating and assessing scientific hypotheses. More generally, it allows users to identify biologically meaningful links between any two sets of articles A and C in PubMed, even when these share no articles or authors in common and represent disparate topics or disciplines. The key idea is to relate the two sets of articles via title words and phrases (B-terms) that they share. We have created a free, public web-based version of the two-node search tool (http://arrowsmith.psych.uic.edu), have described its development and implementation, and have presented analyses of individual two-node searches. In this paper, we provide an updated tutorial intended for end-users, that covers the use of the tool for a variety of potential scientific use case scenarios. For example, one can assess a recent experimental, clinical or epidemiologic finding that connects two disparate fields of inquiry--identifying likely mechanisms to explain the finding, and choosing promising follow-up lines of investigation. Alternatively, one can assess whether the existing scientific literature lends indirect support to a hypothesis posed by the user that has not yet been investigated. One can also employ two-node searches to search for novel hypotheses. Arrowsmith provides a service that cannot be carried out feasibly via standard PubMed searches or by other available text mining tools.

Indexed as

Information Storage and RetrievalMEDLINEAbstracting and IndexingAlgorithmsInternetNatural Language ProcessingPattern Recognition, AutomatedPubMedSoftwareUser-Computer Interface

Identifiers

PMID19185946
PMCPMC2693227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.