ReviewHandbook of experimental pharmacology2009
The road to discovery of neuronal nicotinic cholinergic receptor subtypes.
Review in Handbook of experimental pharmacology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- From squid giant axon to automated patch-clamp: electrophysiology in venom and antivenom research.Frontiers in pharmacology · 2023Review
- Dopamine D2 autoreceptor interactome: Targeting the receptor complex as a strategy for treatment of substance use disorder.Pharmacology & therapeutics · 2020Review
- Differential effects of withdrawal from intermittent and continuous nicotine exposure on reward deficit and somatic aspects of nicotine withdrawal and expression of α4β2* nAChRs in Wistar male rats.Pharmacology, biochemistry, and behavior · 2018Article
- Merging old and new perspectives on nicotinic acetylcholine receptors.Biochemical pharmacology · 2014Review
- Genetics and smoking.Current addiction reports · 2014Article
- Nicotinic receptor antagonists as treatments for nicotine abuse.Advances in pharmacology (San Diego, Calif.) · 2014Review
- Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma.PloS one · 2014Article
- Dopamine D₂ and acetylcholine α7 nicotinic receptors have subcellular distributions favoring mediation of convergent signaling in the mouse ventral tegmental area.Neuroscience · 2013Article
- Mice lacking the β4 subunit of the nicotinic acetylcholine receptor show memory deficits, altered anxiety- and depression-like behavior, and diminished nicotine-induced analgesia.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2012Article
- Chromosome 20 shows linkage with DSM-IV nicotine dependence in Finnish adult smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2012Article
- Acetylcholine α7 nicotinic and dopamine D2 receptors are targeted to many of the same postsynaptic dendrites and astrocytes in the rodent prefrontal cortex.Synapse (New York, N.Y.) · 2011Article
- Protein kinase C epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Associations of nicotine intake measures with CHRN genes in Finnish smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2011Article
- Historical and current perspective on tobacco use and nicotine addiction.Trends in neurosciences · 2011Review
- Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.Nature genetics · 2010Article
- John Daly's compound, epibatidine, facilitates identification of nicotinic receptor subtypes.Journal of molecular neuroscience : MN · 2010Article
- Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15.Human molecular genetics · 2009Article
- Nicotinic receptor-based therapeutics and candidates for smoking cessation.Biochemical pharmacology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The discovery that mammalian brain expresses the mRNAs for nine different nicotinic cholinergic receptor subunits (alpha2-alpha7, beta2-beta4) that form functional receptors when expressed in Xenopus laevis oocytes suggests that many different types of nicotinic cholinergic receptors (nAChRs) might be expressed in the mammalian brain., Using an historical approach, this chapter reviews some of the progress made in identifying the nAChR subtypes that seem to play a vital role in modulating dopaminergic function. nAChR subtypes that are expressed in dopamine neurons, as well as neurons that interact with dopamine neurons (glutamatergic, GABAergic), serve as the focus of this review. Subjects that are highlighted include the discovery of a low affinity alpha4beta2* nAChR, the identity of recently characterized alpha6* nAChRs, and the finding that these alpha6* receptors have the highest affinity for receptor activation of any of the native receptors that have been characterized to date. Topics that have been ignored in other recent reviews of this area, such as the discovery and potential importance of alternative transcripts, are presented along with a discussion of their potential importance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.