Evidence map›Paper›PMID 19184441›Full record

ReviewNeuropsychology review2009

Typologies of alcohol dependence. From Jellinek to genetics and beyond.

Lorenzo Leggio, George A Kenna, Miriam Fenton, Erica Bonenfant, Robert M Swift

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neuropsychology review, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Trial
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  5. A human laboratory pilot study with baclofen in alcoholic individuals.Pharmacology, biochemistry, and behavior · 2013
    Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Classification of Alcohol Use Disorder With Explainable AI.Alcohol, clinical & experimental research · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Comparing the psychometric properties of reward and relief drinking measures.Experimental and clinical psychopharmacology · 2024
    Article
  17. Article
  18. Observational
  19. Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lorenzo LeggioCenter for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, Box G S 121-4, Providence, RI 02912, USA. Lorenzo_Leggio@brown.edu
George A Kenna
Miriam Fenton
Erica Bonenfant
Robert M Swift

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of typology research is to identify subtypes of alcohol dependent (AD) patients sharing fundamental characteristics and try to match each subtype, with the most precise treatment strategy. This review provides a comprehensive history of the literature on alcohol dependent subtypes starting from the earliest attempt made by Jellinek. The binary models identified most closely with Cloninger and Babor as well as the successively more complex classifications are discussed. Typology classification potentially useful in guiding the treatment of AD patients, especially in the case of the serotonergic medications. Contrasting data suggests that other factors could influence the response to a medication and/or that more complex typologies should be identified. In summary, typology models may assist in the ascertainment criteria for clinical trials performed in behavioral and pharmacotherapeutic interventions. Greater emphasis, however, must be made to more clearly delineate this field of research, while moving toward more standardized typologies.

Indexed as

Age of OnsetAlcohol DrinkingAlcoholismComorbidityFamilyGenetic Predisposition to DiseaseHumansMental DisordersNarcotic AntagonistsSerotonin AgentsSex FactorsNarcotic AntagonistsSerotonin Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.