Evidence map›Paper›PMID 19184381›Full record

ArticleJournal of clinical immunology2009

Clinical characteristics and outcomes of primary immunodeficiencies in Thai children: an 18-year experience from a tertiary care center.

P Benjasupattananan, T Simasathein, P Vichyanond, V Leungwedchakarn, N Visitsunthorn, P Pacharn, O Jirapongsananuruk

Abstract read
In one paragraph

Article in Journal of clinical immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Clinical and demographic pattern of chronic granulomatous disease (CGD) from a multicenter perspective: Malaysia's experience over 26 years.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

P BenjasupattanananDivision of Allergy and Immunology, Department of Pediatrics, Siriraj Hospital Mahidol University, 2 Prannok Rd, Bangkoknoi, Bangkok 10700, Thailand.
T Simasathein
P Vichyanond
V Leungwedchakarn
N Visitsunthorn
P Pacharn
O Jirapongsananuruk

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEarly diagnosis and treatment are keys to improve survival of patients with primary immunodeficiency diseases (PID). The clinical characteristics of these patients in Thailand were not well defined.

objectiveThis study aimed to determine the clinical characteristics and outcomes of patients with PID in Thailand.

methodsMedical records of PID patients in the past 18 years were reviewed.

resultsSixty-seven children were registered. Antibody deficiencies were the most common PID (52.2%), followed by combined T cell and B cell immunodeficiencies (25.4%), other well-defined immunodeficiency syndromes (11.9%), and phagocytic defects (10.4%). The most common presentations of antibody deficiencies, combined T cell and B cell immunodeficiencies, and phagocytic defects were infection in the upper respiratory tract (74.3%), gastrointestinal tract (82.4%), and skin (85.7%), respectively. The highest mortality rate (52.9%) was found in severe combined immunodeficiency.

conclusionThese results provide clinical features of PID in Thailand. Knowing these features will lead to prompt diagnosis and appropriate management.

Indexed as

Age of OnsetBone Marrow TransplantationChildChild, PreschoolDNA Mutational AnalysisEarly DiagnosisFemaleHumansImmunoglobulins, IntravenousImmunologic Deficiency SyndromesInfantInfant, NewbornMaleOpportunistic InfectionsPrevalenceRespiratory Tract InfectionsImmunoglobulins, Intravenous

Identifiers

PMID19184381
PMCPMC7102384

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.