ArticleDevelopment genes and evolution2009
Conserved and novel gene expression between regeneration and asexual fission in Nematostella vectensis.
Article in Development genes and evolution, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 65 citations in OpenAlex.
- Reflections on Model Species in Evolutionary Developmental Biology.Results and problems in cell differentiation · 2026Review
- Heterotrophy and symbiosis affect energy reserves for pedal lacerates in the sea anemonePeerJ · 2026Article
- Whole body regeneration deploys a rewired embryonic gene regulatory network logic.Nature communications · 2025Article
- Article
- Fission in a colonial marine invertebrate signifies unique life history strategies rather than being a demographic trait.Scientific reports · 2022Article
- Inheritance of somatic mutations by animal offspring.Science advances · 2022Article
- A pan-metazoan concept for adult stem cells: the wobbling Penrose landscape.Biological reviews of the Cambridge Philosophical Society · 2022Article
- Review
- Hedgehog signaling is required for endomesodermal patterning and germ cell development in the sea anemoneeLife · 2020Article
- What makes flatworms go to pieces.Nature · 2019Article
- Inducing Complete Polyp Regeneration from the Aboral Physa of the Starlet Sea Anemone Nematostella vectensis.Journal of visualized experiments : JoVE · 2017Article
- Article
- The rise of the starlet sea anemone Nematostella vectensis as a model system to investigate development and regeneration.Wiley interdisciplinary reviews. Developmental biology · 2016Review
- Identification of differentially expressed genes from multipotent epithelia at the onset of an asexual development.Scientific reports · 2016Article
- Diversity of Cnidarian Muscles: Function, Anatomy, Development and Regeneration.Frontiers in cell and developmental biology · 2016Review
- Characterization of Morphological and Cellular Events Underlying Oral Regeneration in the Sea Anemone, Nematostella vectensis.International journal of molecular sciences · 2015Article
- A staging system for the regeneration of a polyp from the aboral physa of the anthozoan Cnidarian Nematostella vectensis.Developmental dynamics : an official publication of the American Association of Anatomists · 2013Article
- Microinjection of mRNA or morpholinos for reverse genetic analysis in the starlet sea anemone, Nematostella vectensis.Nature protocols · 2013Article
- Characterizing the spatiotemporal expression of RNAs and proteins in the starlet sea anemone, Nematostella vectensis.Nature protocols · 2013Article
- A report from the second Nematostella vectensis research conference.Development genes and evolution · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to work in model systems (e.g., flies and mice), the molecular mechanisms of embryogenesis are known in exquisite detail. However, these organisms are incapable of asexual reproduction and possess limited regenerative abilities. Thus, the mechanisms of alternate developmental trajectories and their relation to embryonic mechanisms remain understudied. Because these developmental trajectories are present in a diverse group of animal phyla spanning the metazoan phylogeny, including cnidarians, annelids, and echinoderms, they are likely to have played a major role in animal evolution. The starlet sea anemone Nematostella vectensis, an emerging model system, undergoes larval development, asexual fission, and complete bi-directional regeneration in the field and laboratory. In order to investigate to what extent embryonic patterning mechanisms are utilized during alternate developmental trajectories, we examined expression of developmental regulatory genes during regeneration and fission. When compared to previously reported embryonic expression patterns, we found that all genes displayed some level of expression consistent with embryogenesis. However, five of seven genes investigated also displayed striking differences in gene expression between one or more developmental trajectory. These results demonstrate that alternate developmental trajectories utilize distinct molecular mechanisms upstream of major developmental regulatory genes such as fox, otx, and Hox-like.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.