Trial reportEuropean journal of applied physiology2009
Cumulative effects of consecutive running sessions on hemolysis, inflammation and hepcidin activity.
Trial report in European journal of applied physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Factors Influencing the Hepcidin Response to Exercise: An Individual Participant Data Meta-analysis.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- The relationship between hemoglobin andPloS one · 2023Pooled it
- Association of Serum Hepcidin Levels with Aerobic and Resistance Exercise: A Systematic Review.Nutrients · 2021Pooled it
- Effects of exercise in cool versus hot conditions on pathways of gut permeability, systemic inflammation, and iron homeostasis in female athletes.Physiological reports · 2026Trial
- Iron Supplementation during Three Consecutive Days of Endurance Training Augmented Hepcidin Levels.Nutrients · 2017Trial
- Relationship between the Ingestion of a Polyphenol-Rich Drink, Hepcidin Hormone, and Long-Term Training.Molecules (Basel, Switzerland) · 2016Trial
- Seven days of high carbohydrate ingestion does not attenuate post-exercise IL-6 and hepcidin levels.European journal of applied physiology · 2016Trial
- Article
- International society of sports nutrition position stand: nutritional concerns of the female athlete.Journal of the International Society of Sports Nutrition · 2023Review
- Article
- Six weeks of dynamic apnoeic training stimulates erythropoiesis but does not increase splenic volume.European journal of applied physiology · 2021Article
- Article
- Epidemiological, biological and clinical update on exercise-induced hemolysis.Annals of translational medicine · 2019Review
- Effects of diet before endurance exercise on hepcidin response in young untrained females.Journal of exercise nutrition & biochemistry · 2018Article
- Changes in iron metabolism during prolonged repeated walking exercise in middle-aged men and women.European journal of applied physiology · 2018Article
- Heme oxygenase activity increases after exercise in healthy volunteers.Free radical research · 2018Article
- Elevated Serum Hepcidin Levels during an Intensified Training Period in Well-Trained Female Long-Distance Runners.Nutrients · 2017Article
- Single dose of intra-muscular platelet rich plasma reverses the increase in plasma iron levels in exercise-induced muscle damage: A pilot study.Journal of sport and health science · 2016Article
- Acute dietary carbohydrate manipulation and the subsequent inflammatory and hepcidin responses to exercise.European journal of applied physiology · 2015Article
- Timing of post-exercise carbohydrate ingestion: influence on IL-6 and hepcidin responses.European journal of applied physiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effect of two running sessions completed within a 12-h period on hemolysis, inflammation, and hepcidin activity in endurance athletes was investigated. Ten males completed two experimental trials in a randomized, counterbalanced order. The two trials included (a) a one-running-session trial (T1) including 10 x 1 km interval repeats (90% peak VO2 velocity), and (b) a two-running-session trial (T2), comprising a continuous 10-km run (70% peak VO2 velocity), and a 10 x 1 km interval run (90% peak VO2 velocity) completed 12 h later. Interleukin-6 (IL-6), free hemoglobin (Hb), haptoglobin (Hp), iron, ferritin, and hepcidin were assessed post-exercise. After the T1 and T2 interval runs, free Hb was significantly increased and Hp significantly decreased (p <or= 0.05), with a cumulative effect shown in T2 after the second run (p <or= 0.05). The IL-6, serum iron, ferritin, and hepcidin activity were increased after each running session (p <or= 0.05), with no cumulative effect in T2. In conclusion, a cumulative effect of two running sessions on hemolysis was shown, but no similar effect with inflammation and hepcidin activity was evident.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.