ArticleEuropean journal of nuclear medicine and molecular imaging2009
Aortic inflammation, as assessed by hybrid FDG-PET/CT imaging, is associated with enhanced aortic stiffness in addition to concurrent calcification.
Article in European journal of nuclear medicine and molecular imaging, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Biomarkers of Cardiovascular Risk in Patients With Rheumatoid Arthritis: Results From the TARGET Trial.Journal of the American Heart Association · 2024Trial
- Volume of the proximal half of the thoracic aorta is the most comprehensive FDG-PET/CT indicator of arterial aging throughout adulthood.European journal of hybrid imaging · 2023Article
- Association between urinary biomarkers of polycyclic aromatic hydrocarbons and severe abdominal aortic calcification in adults: data from the National Health and Examination Nutrition Survey.BMC cardiovascular disorders · 2023Article
- Assessment of aortic stiffness in computed tomography - methodology of radiological examination from 2000 to 2020.Polish journal of radiology · 2022Review
- Multiparametric Molecular Imaging of Atherosclerosis: Insights Into Disease Pathology and Risk.Circulation. Cardiovascular imaging · 2020Article
- Association of aortic vascular uptake ofEuropean journal of nuclear medicine and molecular imaging · 2019Observational
- Molecular imaging of endothelial activation and mineralization in a mouse model of accelerated atherosclerosis.EJNMMI research · 2019Article
- Performance Evaluation of a Dedicated Preclinical PET/CT System for the Assessment of Mineralization Process in a Mouse Model of Atherosclerosis.Molecular imaging and biology · 2018Article
- Vascular inflammation and aortic stiffness: potential mechanisms of increased vascular risk in chronic obstructive pulmonary disease.Respiratory research · 2018Observational
- Arterial Inflammation Detected WithArthritis & rheumatology (Hoboken, N.J.) · 2018Article
- Cross-sectional variations of white and grey matter in older hypertensive patients with subjective memory complaints.NeuroImage. Clinical · 2018Article
- Resveratrol Decreases TXNIP mRNA and Protein Nuclear Expressions With an Arterial Function Improvement in Old Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016Article
- Influence of Thoracic Aortic Inflammation and Calcifications on Arterial Stiffness and Cardiac Function in Older Subjects.The journal of nutrition, health & aging · 2016Article
- PET imaging of inflammation in atherosclerosis.Nature reviews. Cardiology · 2014Review
- Cytomegalovirus seropositivity is associated with increased arterial stiffness in patients with chronic kidney disease.PloS one · 2013Article
- Caloric restriction: powerful protection for the aging heart and vasculature.American journal of physiology. Heart and circulatory physiology · 2011Article
- Imaging of coronary inflammation with FDG-PET: feasibility and clinical hurdles.Current cardiology reports · 2011Review
- Beyond stenosis: further progress in multi-modal evaluation of carotid disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2011Article
- Noninvasive Positron Emission Tomography Imaging of Coronary Arterial Inflammation.Current cardiovascular imaging reports · 2011Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo analyse the relationship between: (i) aortic pulse wave velocity (PWV), an index of aortic stiffness with strong prognostic significance, and (ii) aortic calcification and inflammation, which were quantified by hybrid imaging with X-ray computed tomography (CT) and (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET).
methodsCentral aortic (carotid-femoral) and peripheral (carotid-brachial and femoral-tibial) PWV were recorded in 26 patients, who had been routinely referred for dual FDG-PET/CT imaging.
resultsIn univariate analyses, central aortic PWV was strongly linked to the volume of calcifications (VCa) and an enhanced FDG activity, when determined by averaging standardized uptake values (SUV(max)). By multivariate stepwise analysis including age and gender, both VCa (p < 0.0001) and SUV(max) (p < 0.01) were significant determinants of PWV explaining 61% and 11% of its variability.
conclusionAortic inflammation, assessed by hybrid FDG-PET/CT imaging, is associated with an enhanced aortic stiffness, in addition to the concurrent impact of calcifications.
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