ReviewIntensive care medicine2009
Controversies in paediatric continuous renal replacement therapy.
Review in Intensive care medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- Regional citrate anticoagulation for pediatric CRRT using integrated citrate software and physiological sodium concentration solutions.Pediatric nephrology (Berlin, Germany) · 2014Trial
- An epidemiological assessment of hemodialysis, continuous kidney replacement therapy, and peritoneal dialysis in pediatric acute kidney injury patients.Renal failure · 2026Article
- Effectiveness and feasibility of continuous renal replacement therapy for acute kidney injury in neonates weighing 3 kg or less: a two-centre, retrospective study.BMJ paediatrics open · 2024Article
- Continuous renal replacement therapy in neonates and children: what does the pediatrician need to know? An overview from the Critical Care Nephrology Section of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).European journal of pediatrics · 2024Review
- Continuous Kidney Replacement Therapy Practices in Pediatric Intensive Care Units Across Europe.JAMA network open · 2022Article
- Extracorporeal renal and liver support in pediatric acute liver failure.Pediatric nephrology (Berlin, Germany) · 2021Review
- Association of Fluid Balance and Survival of Pediatric Patients Treated With Extracorporeal Membrane Oxygenation.Frontiers in pediatrics · 2021Article
- Regional citrate anticoagulation for continuous renal replacement therapy in pediatric patients with liver failure.PloS one · 2017Article
- Novel Use of an Ultrafiltration Device as an Alternative Method for Fluid Removal in Critically Ill Pediatric Patients with Cardiac Disease: A Case Series.Pediatric reports · 2016Article
- Biology of sepsis: its relevance to pediatric nephrology.Pediatric nephrology (Berlin, Germany) · 2014Review
- Impact of fluid balance on outcome of adult patients treated with extracorporeal membrane oxygenation.Intensive care medicine · 2014Observational
- Continuous renal replacement therapy in neonates weighing less than 3 kg.Korean journal of pediatrics · 2012Article
- Development of an accurate fluid management system for a pediatric continuous renal replacement therapy device.ASAIO journal (American Society for Artificial Internal Organs : 1992)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundContinuous renal replacement therapy (CRRT) is an invaluable means of supporting critically ill children with many illnesses, including acute renal failure, drug intoxication, inborn errors of metabolism, and multiorgan failure. However, the ideal method of applying the technique is unknown. DISCUSSION: The indications for initiation of CRRT, mode, dose, and means of anticoagulating the circuit to prolong filter life are all subjects of controversy. The formation of a prospective, multicentre paediatric CRRT registry has been a major step forward but large, randomised trials of the sort that exist in adult medicine are lacking. This review describes the basic technique of CRRT, highlights the differences between adult and paediatric prescription, and elaborates on the main controversies in the application of CRRT in children.
conclusionsCurrent evidence suggests that early initiation of CRRT before the onset of substantial fluid overload, considering continuous haemofiltration in disease states such as respiratory failure following stem cell transplantation, and the use of continuous haemodialysis and citrate anticoagulation to prolong circuit life may be associated with improved outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.