Evidence map›Paper›PMID 19183763›Full record

ArticleVascular health and risk management2008

Maintenance of improved lipid levels following attendance at a cardiovascular risk reduction clinic: a 10-year experience.

Glen J Pearson, Kari L Olson, Nicole E Panich, Sumit R Majumdar, Ross T Tsuyuki, Dawna M Gilchrist, Ali Damani, Gordon A Francis

Open access · goldAbstract read
In one paragraph

Article in Vascular health and risk management, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Lipid clinics are urgently required in the Iranian public health system.International journal of preventive medicine · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Glen J PearsonDepartment of Medicine, Divisions of Cardiology, Cardiovascular Risk Reduction Clinic, University of Alberta Hospital, Edmonton, Alberta, Canada. glen.pearson@ualberta.ca
Kari L Olson
Nicole E Panich
Sumit R Majumdar
Ross T Tsuyuki
Dawna M Gilchrist
Ali Damani
Gordon A Francis
University of Alberta · CAUniversity of Alberta Hospital · CAAlberta Hospital Edmonton · CAPharmaceutical Biotechnology (Czechia) · CZUniversity of Colorado Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpecialty cardiovascular risk reduction clinics (CRRC) increase the proportion of patients attaining recommended lipid targets; however, it is not known if the benefits are sustained after discharge. We evaluated the impact of a CRRC on lipid levels and assessed the long-term effect of a CRRC in maintaining improved lipid levels following discharge.

methodsThe medical records of consecutive dyslipidemic patients discharged > 6 months from a tertiary hospital CRRC from January 1991 to January 2001 were retrospectively reviewed. The primary outcome was the change in patients' lipid levels between the final CRRC visit and the most recent primary care follow-up. A worst-case analysis was conducted to evaluate the potential impact of the patients in whom the follow-up lipid profiles post-discharge from the CRRC were not obtained.

resultsWithin the CRRC (median follow-up = 1.28 years in 1064 patients), we observed statistically significant improvements in all lipid parameters. In the 411 patients for whom post-discharge lipid profiles were available (median follow-up = 2.41 years), there were no significant differences observed in low-density lipoprotein-cholesterol, total cholesterol (TC), or triglycerides since CRRC discharge; however, there were small improvements in high-density lipoprotein-cholesterol (HDL-C) and TC:HDL ratio (p < 0.05 for both). The unadjusted worst-case analysis (653 patients with no follow-up lipid profiles) demonstrated statistically significant worsening of all lipid parameters between CRRC discharge and the most recent follow-up. However, when the change in lipid parameters between the baseline and the most recent follow-up was assessed in this analysis, the changes in all lipid parameters were significantly improved (p < 0.05).

conclusionsThis study demonstrates that a CRRC can improve lipid levels and suggests that these benefits are sustained once patients are returned to the care of their primary physician.

Indexed as

Outpatient Clinics, HospitalPrimary Health CareRisk Reduction BehaviorCardiovascular DiseasesDyslipidemiasHumansLipidsPatient DischargeRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeLipidscardiovascular risk factorsdyslipidemiaoutcomespharmacotherapysecondary prevention

Identifiers

PMID19183763
PMCPMC2605345
OpenAlexW1939039978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.