ArticleSIAM journal on applied mathematics2009
ANALYSIS OF HEPATITIS C VIRUS INFECTION MODELS WITH HEPATOCYTE HOMEOSTASIS.
Article in SIAM journal on applied mathematics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Topological Stability and Transcritical Bifurcations in a Target-Cell-Limited Model of HBV-HDV Viral Interference.Viruses · 2026Article
- INHERITANCE OF INTRACELLULAR VIRAL RNA IN A MULTISCALE MODEL OF HEPATITIS C INFECTION.SIAM journal on applied mathematics · 2026Article
- Stability of a diffusive-delayed HCV infection model with general cell-to-cell incidence function incorporating immune response and cell proliferation.Theory in biosciences = Theorie in den Biowissenschaften · 2023Article
- Topological data analysis of antibody dynamics of severe and non-severe patients with COVID-19.Mathematical biosciences · 2023Article
- Multiscale model of hepatitis C virus dynamics in plasma and liver following combination therapy.CPT: pharmacometrics & systems pharmacology · 2021Article
- Controlling of pandemic COVID-19 using optimal control theory.Results in physics · 2021Article
- Mathematical analysis and simulation of a stochastic COVID-19 Lévy jump model with isolation strategy.Results in physics · 2021Article
- In-host Mathematical Modelling of COVID-19 in Humans.Annual reviews in control · 2020Article
- A New Model for the Dynamics of Hepatitis C Infection: Derivation, Analysis and Implications.Viruses · 2018Review
- A New Age-Structured Multiscale Model of the Hepatitis C Virus Life-Cycle During Infection and Therapy With Direct-Acting Antiviral Agents.Frontiers in microbiology · 2018Article
- The Role of Infected Cell Proliferation in the Clearance of Acute HBV Infection in Humans.Viruses · 2017Article
- In-host modeling.Infectious Disease Modelling · 2017Article
- Modelling hepatitis C therapy--predicting effects of treatment.Nature reviews. Gastroenterology & hepatology · 2015Review
- Ebola virus infection modeling and identifiability problems.Frontiers in microbiology · 2015Article
- ModeLang: a new approach for experts-friendly viral infections modeling.Computational and mathematical methods in medicine · 2013Article
- Modeling quasispecies and drug resistance in hepatitis C patients treated with a protease inhibitor.Bulletin of mathematical biology · 2012Article
- Analysis of the virus dynamics model reveals that early treatment of HCV infection may lead to the sustained virological response.PloS one · 2012Article
- Hepatitis C Viral Kinetics in the Era of Direct Acting Antiviral Agents and IL28B.Current hepatitis reports · 2011Article
- A perspective on modelling hepatitis C virus infection.Journal of viral hepatitis · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Recently, we developed a model for hepatitis C virus (HCV) infection that explicitly includes proliferation of infected and uninfected hepatocytes. The model predictions agree with a large body of experimental observations on the kinetics of HCV RNA change during acute infection, under antiviral therapy, and after the cessation of therapy. Here we mathematically analyze and characterize both the steady state and dynamical behavior of this model. The analyses presented here are important not only for HCV infection but should also be relevant for modeling other infections with hepatotropic viruses, such as hepatitis B virus.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.