ArticleJournal of bacteriology2009
The putrescine Importer PuuP of Escherichia coli K-12.
Article in Journal of bacteriology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Research progress on the microbial metabolism and transport of polyamines and their roles in animal gut homeostasis.Journal of animal science and biotechnology · 2025Review
- Association Analysis of the Genomic and Functional Characteristics of HalotolerantMicroorganisms · 2025Article
- Contact-dependent growth inhibition (CDI) systems deploy a large family of polymorphic ionophoric toxins for inter-bacterial competition.PLoS genetics · 2024Article
- Salmonella Typhimurium exploits host polyamines for assembly of the type 3 secretion machinery.PLoS biology · 2024Article
- Polyamine signaling communications play a key role in regulating the pathogenicity ofMicrobiology spectrum · 2023Article
- Exploring the Potential of a Genome-ReducedInternational journal of molecular sciences · 2023Article
- Article
- Isolation of the high polyamine-producing bacteriumBioscience of microbiota, food and health · 2023Article
- Polyamine and Ethanolamine Metabolism in Bacteria as an Important Component of Nitrogen Assimilation for Survival and Pathogenicity.Medical sciences (Basel, Switzerland) · 2022Review
- Improvement of putrescine production through the arginine decarboxylase pathway in Escherichia coli K-12.AMB Express · 2021Article
- The citrus plant pathogenBiochemistry and biophysics reports · 2021Article
- PaeA (YtfL) protects from cadaverine and putrescine stress in Salmonella Typhimurium and E. coli.Molecular microbiology · 2021Article
- Effect of Spermidine on Biofilm Formation in Escherichia coli K-12.Journal of bacteriology · 2021Article
- Knowns and Unknowns of Vitamin BEcoSal Plus · 2021Review
- The importance of genetic research on the dominant species of human intestinal indigenous microbiota.Bioscience of microbiota, food and health · 2021Review
- Targeting metabolic driving and intermediate influx in lysine catabolism for high-level glutarate production.Nature communications · 2019Article
- Putrescine Is an Intraspecies and Interkingdom Cell-Cell Communication Signal Modulating the Virulence ofFrontiers in microbiology · 2019Article
- Article
- A Novel Putrescine Exporter SapBCDF of Escherichia coli.The Journal of biological chemistry · 2016Article
- The Metagenome of Utricularia gibba's Traps: Into the Microbial Input to a Carnivorous Plant.PloS one · 2016Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Puu pathway is a putrescine utilization pathway involving gamma-glutamyl intermediates. The genes encoding the enzymes of the Puu pathway form a gene cluster, the puu gene cluster, and puuP is one of the genes in this cluster. In Escherichia coli, three putrescine importers, PotFGHI, PotABCD, and PotE, were discovered in the 1990s and have been studied; however, PuuP had not been discovered previously. This paper shows that PuuP is a novel putrescine importer whose kinetic parameters are equivalent to those of the polyamine importers discovered previously. A puuP(+) strain absorbed up to 5 mM putrescine from the medium, but a DeltapuuP strain did not. E. coli strain MA261 has been used in previous studies of polyamine transporters, but PuuP had not been identified previously. It was revealed that the puuP gene of MA261 was inactivated by a point mutation. When E. coli was grown on minimal medium supplemented with putrescine as the sole carbon or nitrogen source, only PuuP among the polyamine importers was required. puuP was expressed strongly when putrescine was added to the medium or when the puuR gene, which encodes a putative repressor, was deleted. When E. coli was grown in M9-tryptone medium, PuuP was expressed mainly in the exponential growth phase, and PotFGHI was expressed independently of the growth phase.
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